5MV4
ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23)
Summary for 5MV4
Entry DOI | 10.2210/pdb5mv4/pdb |
Descriptor | ACC1 antibody Fab fragment, heavy chain, ACC1 antibody Fab fragment, light chain, synthetic peptide containing the citrullinated collagen type II epitope CII616-639,Collagen alpha-1(II) chain,synthetic peptide containing the citrullinated collagen type II epitope CII616-639, ... (5 entities in total) |
Functional Keywords | anti-citrullinated protein antibody (acpa) fab fragment collagen type ii citrullinated c1 epitope, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 24 |
Total formula weight | 410469.96 |
Authors | Dobritzsch, D.,Holmdahl, R.,Ge, C. (deposition date: 2017-01-15, release date: 2017-07-19, Last modification date: 2024-01-17) |
Primary citation | Ge, C.,Tong, D.,Liang, B.,Lonnblom, E.,Schneider, N.,Hagert, C.,Viljanen, J.,Ayoglu, B.,Stawikowska, R.,Nilsson, P.,Fields, G.B.,Skogh, T.,Kastbom, A.,Kihlberg, J.,Burkhardt, H.,Dobritzsch, D.,Holmdahl, R. Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2:-, 2017 Cited by PubMed: 28679953DOI: 10.1172/jci.insight.93688 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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