4R2A
| Egr1/Zif268 zinc fingers in complex with methylated DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-11 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.591 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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4R2D
| Egr1/Zif268 zinc fingers in complex with formylated DNA | 分子名称: | DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5FC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), Early growth response protein 1, ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-11 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.088 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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4R2P
| Wilms Tumor Protein (WT1) zinc fingers in complex with hydroxymethylated DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5HC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5HC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-12 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.788 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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4QVZ
| FMRP N-terminal domain | 分子名称: | 1,2-ETHANEDIOL, Fragile X mental retardation protein 1 | 著者 | Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T. | 登録日 | 2014-07-16 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.195 Å) | 主引用文献 | Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain. Hum.Mol.Genet., 24, 2015
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4R2C
| Egr1/Zif268 zinc fingers in complex with hydroxymethylated DNA | 分子名称: | DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5HC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5HC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), Early growth response protein 1, ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-11 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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4R2S
| Wilms Tumor Protein (WT1) Q369P zinc fingers in complex with methylated DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5CM)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5CM)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-12 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.489 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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4R2Q
| Wilms Tumor Protein (WT1) zinc fingers in complex with formylated DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*(5FC)P*GP*T)-3'), DNA (5'-D(*TP*AP*(5FC)P*GP*CP*CP*CP*AP*CP*GP*C)-3'), ... | 著者 | Hashimoto, H, Olanrewaju, Y.O, Zheng, Y, Wilson, G.G, Zhang, X, Cheng, X. | 登録日 | 2014-08-12 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes Dev., 28, 2014
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2M2D
| Human programmed cell death 1 receptor | 分子名称: | Programmed cell death protein 1 | 著者 | Veverka, V, Cheng, X, Waters, L.C, Muskett, F.W, Morgan, S, Lesley, A, Griffiths, M, Stubberfield, C, Griffin, R, Henry, A.J, Robinson, M.K, Jansson, A, Ladbury, J.E, Ikemizu, S, Davis, S.J, Carr, M.D. | 登録日 | 2012-12-18 | 公開日 | 2013-02-27 | 最終更新日 | 2013-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and interactions of the human programmed cell death 1 receptor. J.Biol.Chem., 288, 2013
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2MB5
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6B0Q
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5WJQ
| mouseZFP568-ZnF2-11 in complex with DNA | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (28-MER), ZINC ION, ... | 著者 | Patel, A, Cheng, X. | 登録日 | 2017-07-24 | 公開日 | 2018-03-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins. Cell, 173, 2018
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3ICV
| Structural Consequences of a Circular Permutation on Lipase B from Candida Antartica | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase B | 著者 | Horton, J.R, Qian, Z, Jia, D, Lutz, S, Cheng, X. | 登録日 | 2009-07-18 | 公開日 | 2009-10-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Structural redesign of lipase B from Candida antarctica by circular permutation and incremental truncation. J.Mol.Biol., 393, 2009
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3ICW
| Structure of a Circular Permutation on Lipase B from Candida Antartica with Bound Suicide Inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase B, PHOSPHATE ION, ... | 著者 | Horton, J.R, Qian, Z, Jia, D, Lutz, S.A, Cheng, X. | 登録日 | 2009-07-18 | 公開日 | 2009-10-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structural redesign of lipase B from Candida antarctica by circular permutation and incremental truncation. J.Mol.Biol., 393, 2009
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4PBB
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3KV4
| Structure of PHF8 in complex with histone H3 | 分子名称: | 1,2-ETHANEDIOL, FE (II) ION, Histone H3-like, ... | 著者 | Horton, J.R, Upadhyay, A.K, Qi, H.H, Zhang, X, Shi, Y, Cheng, X. | 登録日 | 2009-11-29 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases. Nat.Struct.Mol.Biol., 17, 2010
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4PBA
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3MO0
| Human G9a-like (GLP, also known as EHMT1) in complex with inhibitor E11 | 分子名称: | 1,2-ETHANEDIOL, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ... | 著者 | Chang, Y, Horton, J.R, Cheng, X. | 登録日 | 2010-04-22 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases. J.Mol.Biol., 400, 2010
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3SWR
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6B0O
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6B0P
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6B0R
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6BLW
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3OS5
| SET7/9-Dnmt1 K142me1 complex | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Dnmt1, ... | 著者 | Esteve, P.-O, Chang, Y, Samaranayake, M, Upadhyay, A.K, Horton, J.R, Feehery, G.R, Cheng, X, Pradhan, S. | 登録日 | 2010-09-08 | 公開日 | 2010-12-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat.Struct.Mol.Biol., 18, 2011
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7TXC
| HIC2 zinc finger domain in complex with the DNA binding motif-2 of the BCL11A enhancer | 分子名称: | DNA (5'-D(*AP*CP*TP*GP*TP*TP*GP*GP*CP*AP*TP*TP*AP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*TP*AP*AP*TP*GP*CP*CP*AP*AP*CP*AP*GP*T)-3'), Hypermethylated in cancer 2 protein, ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2022-02-08 | 公開日 | 2022-06-01 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | 主引用文献 | HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nat.Genet., 54, 2022
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5Z02
| Crystal structure of HIS6-tagged Mdm2 with nutlin-3a | 分子名称: | 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2 | 著者 | Su, Z.D, Cheng, X.Y, Chen, R, Pi, N. | 登録日 | 2017-12-18 | 公開日 | 2018-01-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure of HIS6-tagged Mdm2 with nutlin-3a to be published
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