3KV4

Structure of PHF8 in complex with histone H3

Summary for 3KV4

• Entry DOI: 10.2210/pdb3kv4/pdb
• Related: 3KV5 3KV6 3KV9 3KVA 3KVB
• Descriptor: PHD finger protein 8, Histone H3-like, ZINC ION, ... (8 entities in total)
• Functional Keywords: epigenetics, histone code, covalent histone modifications, jumonji demethylase, mental retardation, metal-binding, zinc, zinc-finger, h3k4me3 binding protein, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9UPP1 Q6NXT2
• Total number of polymer chains: 2
• Total formula weight: 55434.46

Authors

Horton, J.R.,Upadhyay, A.K.,Qi, H.H.,Zhang, X.,Shi, Y.,Cheng, X. (deposition date: 2009-11-29, release date: 2009-12-22, Last modification date: 2023-09-06)

• Primary citation: Horton, J.R.,Upadhyay, A.K.,Qi, H.H.,Zhang, X.,Shi, Y.,Cheng, X.; Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.; Nat.Struct.Mol.Biol., 17:38-43, 2010; PubMed: 20023638; DOI: 10.1038/nsmb.1753

Experimental method

X-RAY DIFFRACTION (2.19 Å)