3OS5
SET7/9-Dnmt1 K142me1 complex
Summary for 3OS5
Entry DOI | 10.2210/pdb3os5/pdb |
Related | 3CBM 3CBO 3CBP |
Descriptor | Histone-lysine N-methyltransferase SETD7, Dnmt1, BETA-MERCAPTOETHANOL, ... (7 entities in total) |
Functional Keywords | epigenetic modification, set domain, protein lysine methyltransferase, dnmt1, lysine mono-methylation, k142, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: Q8WTS6 |
Total number of polymer chains | 2 |
Total formula weight | 30254.72 |
Authors | Esteve, P.-O.,Chang, Y.,Samaranayake, M.,Upadhyay, A.K.,Horton, J.R.,Feehery, G.R.,Cheng, X.,Pradhan, S. (deposition date: 2010-09-08, release date: 2010-12-15, Last modification date: 2023-09-06) |
Primary citation | Esteve, P.O.,Chang, Y.,Samaranayake, M.,Upadhyay, A.K.,Horton, J.R.,Feehery, G.R.,Cheng, X.,Pradhan, S. A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat.Struct.Mol.Biol., 18:42-48, 2011 Cited by PubMed: 21151116DOI: 10.1038/nsmb.1939 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.69 Å) |
Structure validation
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