3OS5

SET7/9-Dnmt1 K142me1 complex

Summary for 3OS5

Entry DOI	10.2210/pdb3os5/pdb
Related	3CBM 3CBO 3CBP
Descriptor	Histone-lysine N-methyltransferase SETD7, Dnmt1, BETA-MERCAPTOETHANOL, ... (7 entities in total)
Functional Keywords	epigenetic modification, set domain, protein lysine methyltransferase, dnmt1, lysine mono-methylation, k142, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q8WTS6
Total number of polymer chains	2
Total formula weight	30254.72
Authors	Esteve, P.-O.,Chang, Y.,Samaranayake, M.,Upadhyay, A.K.,Horton, J.R.,Feehery, G.R.,Cheng, X.,Pradhan, S. (deposition date: 2010-09-08, release date: 2010-12-15, Last modification date: 2023-09-06)
Primary citation	Esteve, P.O.,Chang, Y.,Samaranayake, M.,Upadhyay, A.K.,Horton, J.R.,Feehery, G.R.,Cheng, X.,Pradhan, S. A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat.Struct.Mol.Biol., 18:42-48, 2011 Cited by PubMed: 21151116 DOI: 10.1038/nsmb.1939 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.69 Å)

Structure validation