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PDB: 1379 件
7UIK
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BU of 7uik by Molmil
Mediator-PIC Early (Tail A + Upstream DNA & Activator)
分子名称: DNA (37-MER), DNA (38-MER), Mediator of RNA polymerase II transcription subunit 14, ...
著者Gorbea Colon, J.J, Chen, S.-F, Tsai, K.L, Murakami, K.
登録日2022-03-29
公開日2023-03-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structural basis of a transcription pre-initiation complex on a divergent promoter.
Mol.Cell, 83, 2023
3OSG
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BU of 3osg by Molmil
The structure of protozoan parasite Trichomonas vaginalis Myb2 in complex with MRE-1-12 DNA
分子名称: 5'-D(*AP*AP*AP*TP*AP*TP*CP*GP*TP*TP*AP*T)-3', 5'-D(*AP*TP*AP*AP*CP*GP*AP*TP*AP*TP*TP*T)-3', MYB21
著者Jiang, I, Tsai, C.K, Chen, S.C, Wang, S.H, Amiraslanov, I, Chang, C.F, Wu, W.J, Tai, J.H, Liaw, Y.C, Huang, T.H.
登録日2010-09-09
公開日2011-08-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Molecular basis of the recognition of the ap65-1 gene transcription promoter elements by a Myb protein from the protozoan parasite Trichomonas vaginalis.
Nucleic Acids Res., 39, 2011
6JLF
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BU of 6jlf by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae D179A mutation - HR
分子名称: Bestrophin homolog, ZINC ION
著者Kittredge, A, Chen, S, Yang, T.
登録日2019-03-05
公開日2019-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.548 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
7E3X
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BU of 7e3x by Molmil
Crystal structure of SDR family NAD(P)-dependent oxidoreductase from exiguobacterium
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase
著者Chen, L, Tang, J, Yuan, S, Zhang, F, Chen, S.
登録日2021-02-09
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure-guided evolution of a ketoreductase forefficient and stereoselective bioreduction of bulkyalpha-aminobeta-keto esters
Catalysis Science And Technology, 2021
6JFL
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BU of 6jfl by Molmil
Nucleotide-free Mitofusin2 (MFN2)
分子名称: CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ...
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
6JFM
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BU of 6jfm by Molmil
Mitofusin2 (MFN2)_T111D
分子名称: ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2
著者Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S.
登録日2019-02-10
公開日2019-11-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
7SIM
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BU of 7sim by Molmil
Structure of positive allosteric modulator-free active human calcium-sensing receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, L.Y, Zhang, Z, Mosyak, L, Slavkovich, V.N, Liu, J, Ray, K.M, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, V.P, Tan, Y.Z, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, W.A, Potter, C.S, Carragher, B, Graziano, J, Conigrave, A.D, Frank, J, Clarke, O.B, Fan, Q.R.
登録日2021-10-14
公開日2022-01-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Symmetric activation and modulation of the human calcium-sensing receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
6PRW
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BU of 6prw by Molmil
CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS
分子名称: Propionyl-CoA carboxylase subunit beta, {4-[(6-chloroquinoxalin-2-yl)oxy]phenyl}acetic acid
著者Reddy, M.C.M, Nian, Z, Michele, S.T.C, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
登録日2019-07-11
公開日2020-07-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献CRYSTAL STRUCTURE OF THE CARBOXYLTRANSFERASE SUBUNIT OF ACC (ACCD6) IN COMPLEX WITH INHIBITOR QUIZALOFOP-P DEVERIVATIVE FROM MYCOBACTERIUM TUBERCULOSIS
To Be Published
7SIL
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BU of 7sil by Molmil
Structure of positive allosteric modulator-bound active human calcium-sensing receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine, ...
著者Park, J, Zuo, H, Frangaj, A, Fu, Z, Yen, L.Y, Zhang, Z, Mosyak, L, Slavkovich, V.N, Liu, J, Ray, K.M, Cao, B, Vallese, F, Geng, Y, Chen, S, Grassucci, R, Dandey, V.P, Tan, Y.Z, Eng, E, Lee, Y, Kloss, B, Liu, Z, Hendrickson, W.A, Potter, C.S, Carragher, B, Graziano, J, Conigrave, A.D, Frank, J, Clarke, O.B, Fan, Q.R.
登録日2021-10-14
公開日2022-01-19
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Symmetric activation and modulation of the human calcium-sensing receptor.
Proc.Natl.Acad.Sci.USA, 118, 2021
7EL8
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BU of 7el8 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase
分子名称: Tryptophan--tRNA ligase
著者Xu, M, Chen, S.
登録日2021-04-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENS
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BU of 7ens by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Indolmycin and ATP
分子名称: (5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-04-19
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ELT
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BU of 7elt by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Trp-AMP
分子名称: TRYPTOPHANYL-5'AMP, Tryptophan--tRNA ligase
著者Xu, M, Chen, S.
登録日2021-04-12
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7ENT
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BU of 7ent by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-13 and ATP
分子名称: (5S)-2-(methylamino)-5-[(1R)-1-(4-methyl-1H-indol-3-yl)ethyl]-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-04-19
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
5YAM
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BU of 5yam by Molmil
Solution structure of mice Met-CCL5/RANTES
分子名称: C-C motif chemokine 5
著者Chen, Y.-C, Chen, S.-P, Lee, Y.-Z, Sue, S.-C.
登録日2017-09-01
公開日2018-09-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
5Z90
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BU of 5z90 by Molmil
BRD4 Bromodomain 1 with an inhibitor
分子名称: 1-ethyl-6-pyrrolidin-1-ylsulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4
著者Xiao, S, Chen, S, Chen, H.
登録日2018-02-01
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献BRD4 Bromodomain 1 with an inhibitor
To Be Published
7DWS
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BU of 7dws by Molmil
The structure of T4 Lysozyme I3C/C54T/R125C/E128C complex with Zinc ions
分子名称: Endolysin, ZINC ION
著者Chen, X, Chen, S.
登録日2021-01-17
公開日2021-06-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Rationally designed protein cross-linked hydrogel for bone regeneration via synergistic release of magnesium and zinc ions.
Biomaterials, 274, 2021
4NFT
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BU of 4nft by Molmil
Crystal structure of human lnkH2B-h2A.Z-Anp32e
分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z
著者Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z.
登録日2013-11-01
公開日2014-04-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z
Cell Res., 24, 2014
8RI9
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BU of 8ri9 by Molmil
Late alpha-Synuclein fibril structure from liquid-liquid phase separations.
分子名称: Alpha-synuclein
著者De Simone, A, Barritt, J.D, Chen, S, Cascella, R, Cecchi, C, Bigi, A, Jarvis, J.A, Chiti, F, Dobson, C.M, Fusco, G.
登録日2023-12-18
公開日2024-03-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure-Toxicity Relationship in Intermediate Fibrils from alpha-Synuclein Condensates.
J.Am.Chem.Soc., 146, 2024
7EV3
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BU of 7ev3 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-10 and ATP
分子名称: (5S)-5-[(1R)-1-(4-fluoranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
7EV2
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BU of 7ev2 by Molmil
Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-11 and ATP
分子名称: (5S)-5-[(1R)-1-(4-chloranyl-1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4-one, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, M, Chen, S.
登録日2021-05-20
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.
Acs Chem.Biol., 17, 2022
5Z8R
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BU of 5z8r by Molmil
BRD4 Bromodomain 1 with an inhibitor
分子名称: 1-ethyl-6-[(3S)-3-oxidanylpiperidin-1-yl]sulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4
著者Xiao, S, Chen, S, Chen, H.
登録日2018-02-01
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献BRD4 Bromodomain 1 with an inhibitor
To Be Published
6IV4
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BU of 6iv4 by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation W252F
分子名称: Bestrophin homolog, ZINC ION
著者Kittredge, A, Chen, S, Yang, T.
登録日2018-12-02
公開日2019-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
6IV1
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BU of 6iv1 by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation I180T
分子名称: Bestrophin homolog, ZINC ION
著者Kittredge, A, Chen, S, Yang, T.
登録日2018-12-02
公開日2019-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
5YUF
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BU of 5yuf by Molmil
Crystal Structure of PML RING tetramer
分子名称: Protein PML, ZINC ION
著者Wang, P, Benhend, S, Wu, H, Breitenbach, V, Zhen, T, Jollivet, F, Peres, L, Li, Y, Chen, S, Chen, Z, de THE, H, Meng, G.
登録日2017-11-22
公開日2018-04-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献RING tetramerization is required for nuclear body biogenesis and PML sumoylation.
Nat Commun, 9, 2018
5Z9K
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BU of 5z9k by Molmil
BRD4 Bromodomain 1 with an inhibitor
分子名称: 1-ethyl-6-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]sulfonyl-benzo[cd]indol-2-one, Bromodomain-containing protein 4
著者Xiao, S, Chen, S, Chen, H.
登録日2018-02-03
公開日2019-02-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献BRD4 Bromodomain 1 with an inhibitor
To Be Published

226707

件を2024-10-30に公開中

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