6IV4
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation W252F
Summary for 6IV4
Entry DOI | 10.2210/pdb6iv4/pdb |
Related | 4wd8 |
Descriptor | Bestrophin homolog, ZINC ION (2 entities in total) |
Functional Keywords | bestrophin-1, homolog, mutation, klebsiella pneumoniae, membrane protein |
Biological source | Klebsiella pneumoniae IS53 |
Total number of polymer chains | 5 |
Total formula weight | 169375.94 |
Authors | Kittredge, A.,Chen, S.,Yang, T. (deposition date: 2018-12-02, release date: 2019-11-13, Last modification date: 2024-05-29) |
Primary citation | Ji, C.,Kittredge, A.,Hopiavuori, A.,Ward, N.,Chen, S.,Fukuda, Y.,Zhang, Y.,Yang, T. Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2:240-240, 2019 Cited by PubMed: 31263784DOI: 10.1038/s42003-019-0433-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.14 Å) |
Structure validation
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