4WD8

Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae

Summary for 4WD8

• Entry DOI: 10.2210/pdb4wd8/pdb
• Related: 4WD7
• Descriptor: Bestrophin domain protein, ZINC ION (3 entities in total)
• Functional Keywords: calcium-activated chloride channel, macular degeneration, single-wavelength anomalous diffraction (sad), sodium channel, pentamer, structural genomics, psi-biology, new york consortium on membrane protein structure, nycomps, membrane protein
• Biological source: Klebsiella pneumoniae UHKPC96
• Total number of polymer chains: 5
• Total formula weight: 170137.35

Authors

Yang, T.,Liu, Q.,Hendrickson, W.A.,New York Consortium on Membrane Protein Structure (NYCOMPS) (deposition date: 2014-09-08, release date: 2014-10-01, Last modification date: 2023-12-27)

• Primary citation: Yang, T.,Liu, Q.,Kloss, B.,Bruni, R.,Kalathur, R.C.,Guo, Y.,Kloppmann, E.,Rost, B.,Colecraft, H.M.,Hendrickson, W.A.; Structure and selectivity in bestrophin ion channels.; Science, 346:355-359, 2014; PubMed: 25324390; DOI: 10.1126/science.1259723

Experimental method

X-RAY DIFFRACTION (2.3 Å)