7EL8

Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase

Summary for 7EL8

Entry DOI	10.2210/pdb7el8/pdb
Descriptor	Tryptophan--tRNA ligase (2 entities in total)
Functional Keywords	aminoacylation, trna-binding, aminoacyl-trna synthetase, atp-binding, ligase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	37380.99
Authors	Xu, M.,Chen, S. (deposition date: 2021-04-09, release date: 2022-02-16, Last modification date: 2023-11-29)
Primary citation	Yang, Y.,Xu, Y.,Yue, Y.,Wang, H.,Cui, Y.,Pan, M.,Zhang, X.,Zhang, L.,Li, H.,Xu, M.,Tang, Y.,Chen, S. Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents. Acs Chem.Biol., 17:39-53, 2022 Cited by PubMed: 34908399 DOI: 10.1021/acschembio.1c00394 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation