7EV3

Crystal structure of Mycobacterium tuberculosis tryptophanyl-tRNA synthetase complexed with Y-10 and ATP

Summary for 7EV3

• Entry DOI: 10.2210/pdb7ev3/pdb
• Related: 7EL8 7ELT 7ENS 7ENT 7EV2
• Descriptor: Tryptophan--tRNA ligase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: trprs, aminoacylation, trna-binding, aminoacyl-trna synthetase, atp-binding, ligase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 38187.76

Authors

Xu, M.,Chen, S. (deposition date: 2021-05-20, release date: 2022-02-16, Last modification date: 2023-11-29)

• Primary citation: Yang, Y.,Xu, Y.,Yue, Y.,Wang, H.,Cui, Y.,Pan, M.,Zhang, X.,Zhang, L.,Li, H.,Xu, M.,Tang, Y.,Chen, S.; Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents.; Acs Chem.Biol., 17:39-53, 2022; PubMed: 34908399; DOI: 10.1021/acschembio.1c00394

Experimental method

X-RAY DIFFRACTION (2.7 Å)