6W5Q
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![BU of 6w5q by Molmil](/molmil-images/mine/6w5q) | Structure of the globular C-terminal domain of P. aeruginosa LpoP | 分子名称: | Peptidoglycan synthase activator LpoP, SULFATE ION, TRIETHYLENE GLYCOL | 著者 | Caveney, N.A, Robb, C.S, Simorre, J.P, Strynadka, N.C.J. | 登録日 | 2020-03-13 | 公開日 | 2020-05-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa. Structure, 28, 2020
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8FX4
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![BU of 8fx4 by Molmil](/molmil-images/mine/8fx4) | GC-C-Hsp90-Cdc37 regulatory complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Guanylyl cyclase C, Heat shock protein HSP 90-beta, ... | 著者 | Caveney, N.A, Garcia, K.C. | 登録日 | 2023-01-23 | 公開日 | 2023-07-12 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism. Elife, 12, 2023
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6N7O
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6NTZ
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![BU of 6ntz by Molmil](/molmil-images/mine/6ntz) | Crystal structure of E. coli PBP5-meropenem | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, D-alanyl-D-alanine carboxypeptidase | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | 登録日 | 2019-01-30 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun, 10, 2019
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6NTW
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![BU of 6ntw by Molmil](/molmil-images/mine/6ntw) | Crystal structure of E. coli YcbB | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Probable L,D-transpeptidase YcbB, SULFATE ION | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | 登録日 | 2019-01-30 | 公開日 | 2019-03-20 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun, 10, 2019
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7KGN
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![BU of 7kgn by Molmil](/molmil-images/mine/7kgn) | S. Typhi YcbB - ertapenem complex | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, L,D-transpeptidase | 著者 | Caveney, N.A, Strynadka, N.C.J. | 登録日 | 2020-10-18 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections. Antimicrob.Agents Chemother., 65, 2021
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7KGM
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![BU of 7kgm by Molmil](/molmil-images/mine/7kgm) | C. rodentium YcbB - ertapenem complex | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Putative exported protein | 著者 | Caveney, N.A, Strynadka, N.C.J. | 登録日 | 2020-10-17 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections. Antimicrob.Agents Chemother., 65, 2021
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7LQ6
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![BU of 7lq6 by Molmil](/molmil-images/mine/7lq6) | CryoEM structure of Escherichia coli PBP1b | 分子名称: | Penicillin-binding protein 1B | 著者 | Caveney, N.A, Workman, S.D, Yan, R, Atkinson, C.E, Yu, Z, Strynadka, N.C.J. | 登録日 | 2021-02-13 | 公開日 | 2021-05-26 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | CryoEM structure of the antibacterial target PBP1b at 3.3 angstrom resolution. Nat Commun, 12, 2021
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7U7N
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![BU of 7u7n by Molmil](/molmil-images/mine/7u7n) | IL-27 quaternary receptor signaling complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | 著者 | Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C. | 登録日 | 2022-03-07 | 公開日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structure of the IL-27 quaternary receptor signaling complex. Elife, 11, 2022
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8EWY
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![BU of 8ewy by Molmil](/molmil-images/mine/8ewy) | Structure of Janus Kinase (JAK) dimer complexed with cytokine receptor intracellular domain | 分子名称: | ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, Interferon lambda receptor 1, ... | 著者 | Caveney, N.A, Saxton, R.A, Waghray, D, Garcia, K.C. | 登録日 | 2022-10-24 | 公開日 | 2023-03-08 | 最終更新日 | 2023-03-22 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | Structural basis of Janus kinase trans-activation. Cell Rep, 42, 2023
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8TLD
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![BU of 8tld by Molmil](/molmil-images/mine/8tld) | |
6ZTG
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![BU of 6ztg by Molmil](/molmil-images/mine/6ztg) | Spor protein DedD | 分子名称: | Cell division protein DedD | 著者 | Pazos, M, Peters, K, Boes, A, Safaei, Y, Kenward, C, Caveney, N.A, Laguri, C, Breukink, E, Strynadka, N.C.J, Simorre, J.P, Terrak, M, Vollmer, W. | 登録日 | 2020-07-20 | 公開日 | 2020-11-11 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli. Mbio, 11, 2020
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8DHA
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8DH8
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![BU of 8dh8 by Molmil](/molmil-images/mine/8dh8) | |
8DH9
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![BU of 8dh9 by Molmil](/molmil-images/mine/8dh9) | |
7UWM
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![BU of 7uwm by Molmil](/molmil-images/mine/7uwm) | Structure of the IL-17A-IL-17RA binary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7UWL
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![BU of 7uwl by Molmil](/molmil-images/mine/7uwl) | Structure of the IL-25-IL-17RB-IL-17RA ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7UWK
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![BU of 7uwk by Molmil](/molmil-images/mine/7uwk) | Structure of the higher-order IL-25-IL-17RB complex | 分子名称: | Interleukin-17 receptor B, Interleukin-25 | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7UWJ
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![BU of 7uwj by Molmil](/molmil-images/mine/7uwj) | Structure of the homodimeric IL-25-IL-17RB binary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor B, Interleukin-25 | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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7UWN
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![BU of 7uwn by Molmil](/molmil-images/mine/7uwn) | Structure of the IL-17A-IL-17RA-IL-17RC ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-17 receptor A, ... | 著者 | Wilson, S.C, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2022-05-03 | 公開日 | 2022-07-27 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Organizing structural principles of the IL-17 ligand-receptor axis. Nature, 609, 2022
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8VSP
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![BU of 8vsp by Molmil](/molmil-images/mine/8vsp) | Cryo-EM structure of human invariant chain in complex with HLA-DQ | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, ... | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2024-01-24 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VBW
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![BU of 8vbw by Molmil](/molmil-images/mine/8vbw) | Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 1 | 著者 | Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J. | 登録日 | 2023-12-12 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1. J.Struct.Biol., 216, 2024
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8VRW
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![BU of 8vrw by Molmil](/molmil-images/mine/8vrw) | Cryo-EM structure of human invariant chain in complex with HLA-DR15 | 分子名称: | HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2024-01-22 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
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8VBV
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![BU of 8vbv by Molmil](/molmil-images/mine/8vbv) | Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Cephalexin) inhibited form | 分子名称: | (2S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Penicillin-binding protein 1 | 著者 | Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J. | 登録日 | 2023-12-12 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1. J.Struct.Biol., 216, 2024
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8VBT
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