6NTZ
Crystal structure of E. coli PBP5-meropenem
Summary for 6NTZ
Entry DOI | 10.2210/pdb6ntz/pdb |
Descriptor | D-alanyl-D-alanine carboxypeptidase, (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid (3 entities in total) |
Functional Keywords | carboxypeptidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 44879.30 |
Authors | Caveney, N.A.,Strynadka, N.C.J.,Caballero, G.,Worrall, L.J. (deposition date: 2019-01-30, release date: 2019-03-20, Last modification date: 2023-10-11) |
Primary citation | Caveney, N.A.,Caballero, G.,Voedts, H.,Niciforovic, A.,Worrall, L.J.,Vuckovic, M.,Fonvielle, M.,Hugonnet, J.E.,Arthur, M.,Strynadka, N.C.J. Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun, 10:1849-1849, 2019 Cited by PubMed: 31015395DOI: 10.1038/s41467-019-09507-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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