8DHA

Leptin-bound leptin receptor complex- focused interaction

Summary for 8DHA

• Entry DOI: 10.2210/pdb8dha/pdb
• EMDB information: 27434
• Descriptor: Leptin receptor, Leptin, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: leptin, receptor, complex, hormone
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 3
• Total formula weight: 143351.75

Authors

Saxton, R.A.,Caveney, N.A.,Garcia, K.C. (deposition date: 2022-06-25, release date: 2023-04-19)

• Primary citation: Saxton, R.A.,Caveney, N.A.,Moya-Garzon, M.D.,Householder, K.D.,Rodriguez, G.E.,Burdsall, K.A.,Long, J.Z.,Garcia, K.C.; Structural insights into the mechanism of leptin receptor activation.; Nat Commun, 14:1797-1797, 2023; PubMed: 37002197; DOI: 10.1038/s41467-023-37169-6

Experimental method

ELECTRON MICROSCOPY (3.8 Å)