8FX4

GC-C-Hsp90-Cdc37 regulatory complex

Summary for 8FX4

Entry DOI	10.2210/pdb8fx4/pdb
EMDB information	29523
Descriptor	Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, Guanylyl cyclase C, ... (4 entities in total)
Functional Keywords	guanylyl cyclase, receptor, heat shock protein, regulation, signaling protein, signaling protein-chaperone complex, signaling protein/chaperone
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	298313.02
Authors	Caveney, N.A.,Garcia, K.C. (deposition date: 2023-01-23, release date: 2023-07-12, Last modification date: 2023-08-23)
Primary citation	Caveney, N.A.,Tsutsumi, N.,Garcia, K.C. Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism. Elife, 12:-, 2023 Cited by PubMed: 37535399 DOI: 10.7554/eLife.86784 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation