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8FX4

GC-C-Hsp90-Cdc37 regulatory complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0005524molecular_functionATP binding
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006457biological_processprotein folding
A0016887molecular_functionATP hydrolysis activity
A0032991cellular_componentprotein-containing complex
A0034605biological_processcellular response to heat
A0042470cellular_componentmelanosome
A0048471cellular_componentperinuclear region of cytoplasm
A0050821biological_processprotein stabilization
A0051082molecular_functionunfolded protein binding
A0097718molecular_functiondisordered domain specific binding
A0120293cellular_componentdynein axonemal particle
A0140662molecular_functionATP-dependent protein folding chaperone
B0005524molecular_functionATP binding
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006457biological_processprotein folding
B0016887molecular_functionATP hydrolysis activity
B0032991cellular_componentprotein-containing complex
B0034605biological_processcellular response to heat
B0042470cellular_componentmelanosome
B0048471cellular_componentperinuclear region of cytoplasm
B0050821biological_processprotein stabilization
B0051082molecular_functionunfolded protein binding
B0097718molecular_functiondisordered domain specific binding
B0120293cellular_componentdynein axonemal particle
B0140662molecular_functionATP-dependent protein folding chaperone
C0005737cellular_componentcytoplasm
C0006457biological_processprotein folding
C0019901molecular_functionprotein kinase binding
C0031072molecular_functionheat shock protein binding
C0050821biological_processprotein stabilization
C0051082molecular_functionunfolded protein binding
C0051087molecular_functionprotein-folding chaperone binding
D0003700molecular_functionDNA-binding transcription factor activity
D0004672molecular_functionprotein kinase activity
D0005524molecular_functionATP binding
D0006355biological_processregulation of DNA-templated transcription
D0006468biological_processprotein phosphorylation
D0009190biological_processcyclic nucleotide biosynthetic process
D0016849molecular_functionphosphorus-oxygen lyase activity
D0035556biological_processintracellular signal transduction
Functional Information from PROSITE/UniProt
site_idPS00298
Number of Residues10
DetailsHSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE
ChainResidueDetails
ATYR33-GLU42

site_idPS00452
Number of Residues24
DetailsGUANYLATE_CYCLASE_1 Guanylate cyclase signature. GVV.GikmprYcLFGDTVNtasrmE
ChainResidueDetails
DGLY908-GLU931

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues23
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
DILE408-LEU431

site_idSWS_FT_FI2
Number of Residues618
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
DARG432-PHE1050

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PDB entries from 2024-07-24

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