7KGN

S. Typhi YcbB - ertapenem complex

Summary for 7KGN

Entry DOI	10.2210/pdb7kgn/pdb
Descriptor	L,D-transpeptidase, (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid (2 entities in total)
Functional Keywords	l, d-transpeptidase, antibiotic, transferase
Biological source	Salmonella enterica
Total number of polymer chains	1
Total formula weight	64744.48
Authors	Caveney, N.A.,Strynadka, N.C.J. (deposition date: 2020-10-18, release date: 2020-11-25, Last modification date: 2023-10-18)
Primary citation	Caveney, N.A.,Serapio-Palacios, A.,Woodward, S.E.,Bozorgmehr, T.,Caballero, G.,Vuckovic, M.,Deng, W.,Finlay, B.B.,Strynadka, N.C.J. Structural and Cellular Insights into the l,d-Transpeptidase YcbB as a Therapeutic Target in Citrobacter rodentium, Salmonella Typhimurium, and Salmonella Typhi Infections. Antimicrob.Agents Chemother., 65:-, 2021 Cited by PubMed: 33139287 DOI: 10.1128/AAC.01592-20 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation