6TZ4
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4Q97
| IgNAR antibody domain C1 | 分子名称: | Novel antigen receptor | 著者 | Feige, J.M, Graewert, M.A, Marcinowski, M, Hennig, J, Behnke, J, Auslaender, D, Herold, E.M, Peschek, J, Castro, C.D, Flajnik, M.F, Hendershot, L.M, Sattler, M, Groll, M, Buchner, J. | 登録日 | 2014-04-29 | 公開日 | 2014-07-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins. Proc.Natl.Acad.Sci.USA, 111, 2014
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7QCD
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7WKV
| Crystal structure of human ALKBH5 in complex with 2-oxoglutarate (2OG) and m6A-containing ssRNA | 分子名称: | 2-OXOGLUTARIC ACID, MANGANESE (II) ION, RNA (5'-R(P*GP*GP*(6MZ)P*C)-3'), ... | 著者 | Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S. | 登録日 | 2022-01-11 | 公開日 | 2022-03-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes. Nucleic Acids Res., 50, 2022
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4QLT
| yCP in complex with tripeptidic epoxyketone inhibitor 2 (PR924) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-[(3-methyl-1H-inden-2-yl)carbonyl]-D-alanyl-N-[(2S,4R)-5-hydroxy-4-methyl-3-oxo-1-phenylpentan-2-yl]-L-tryptophanamide, ... | 著者 | de Bruin, G, Huber, E, Xin, B, van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, van der Marel, G, Groll, M, Overkleeft, H. | 登録日 | 2014-06-13 | 公開日 | 2014-07-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes J.Med.Chem., 57, 2014
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5F5H
| X-ray structure of Roquin ROQ domain in complex with Ox40 hexa-loop RNA motif | 分子名称: | GLYCEROL, RNA (5'-R(P*CP*CP*AP*CP*AP*CP*CP*GP*UP*UP*CP*UP*AP*GP*GP*UP*GP*CP*UP*GP*G)-3'), Roquin-1 | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | 登録日 | 2015-12-04 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40. Nat Commun, 7, 2016
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8FWS
| Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
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5WF2
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8FWT
| Structure of the amino terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
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5F6M
| Isotropic Trypsin Model for Comparison of Diffuse Scattering | 分子名称: | BENZAMIDINE, CALCIUM ION, Cationic trypsin, ... | 著者 | Van Benschoten, A.H, Wall, M.E, Fraser, J.S. | 登録日 | 2015-12-06 | 公開日 | 2016-01-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Measuring and modeling diffuse scattering in protein X-ray crystallography. Proc.Natl.Acad.Sci.USA, 113, 2016
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8FWQ
| Structure of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, ... | 著者 | Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
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7WL0
| Crystal structure of human ALKBH5 in complex with N-oxalylglycine (NOG) and m6A-containing ssRNA | 分子名称: | FORMIC ACID, MANGANESE (II) ION, N-OXALYLGLYCINE, ... | 著者 | Kaur, S, McDonough, M.A, Schofield, C.J, Aik, W.S. | 登録日 | 2022-01-12 | 公開日 | 2022-03-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mechanisms of substrate recognition and N6-methyladenosine demethylation revealed by crystal structures of ALKBH5-RNA complexes. Nucleic Acids Res., 50, 2022
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5ITH
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5ITM
| The structure of truncated histone-like protein | 分子名称: | AbrB family transcriptional regulator | 著者 | Lin, B.L, Chen, C.Y, Huang, C.H, Ko, T.P, Chiang, C.H, Lin, K.F, Chang, Y.C, Lin, P.Y, Tsai, H.H.G, Wang, A.H.J. | 登録日 | 2016-03-17 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA. PLoS ONE, 12, 2017
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8Q6K
| Human IgD Fab in complex with an orthosteric inhibitor of Phl p 7 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Human IgD Fab heavy chain, ... | 著者 | Davies, A.M, Vester, S.K, McDonnell, J.M. | 登録日 | 2023-08-11 | 公開日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor. Antibodies, 12, 2023
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4XHF
| Crystal structure of Shewanella oneidensis NqrC | 分子名称: | FLAVIN MONONUCLEOTIDE, Na-translocating NADH-quinone reductase subunit C NqrC, SODIUM ION | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2015-01-05 | 公開日 | 2015-12-16 | 最終更新日 | 2016-03-16 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm. Microbiologyopen, 5, 2016
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5ZX5
| 3.3 angstrom structure of mouse TRPM7 with EDTA | 分子名称: | CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 7 | 著者 | Zhang, J, Li, Z, Duan, J, Li, J, Hulse, R.E, Santa-Cruz, A, Abiria, S.A, Krapivinsky, G, Clapham, D.E. | 登録日 | 2018-05-18 | 公開日 | 2018-10-17 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7QOA
| Structure of CodB, a cytosine transporter in an outward-facing conformation | 分子名称: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-AMINOPYRIMIDIN-2(1H)-ONE, Cytosine permease, ... | 著者 | Hatton, C.E, Cameron, A.D. | 登録日 | 2021-12-23 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of cytosine transport protein CodB provides insight into nucleobase-cation symporter 1 mechanism. Embo J., 41, 2022
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6HRE
| Paired helical filament from sporadic Alzheimer's disease brain | 分子名称: | Microtubule-associated protein tau | 著者 | Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M. | 登録日 | 2018-09-26 | 公開日 | 2018-10-10 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta Neuropathol., 136, 2018
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7TFQ
| Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK Bound to Copper Ion from Yersinia pestis | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, FORMIC ACID, ... | 著者 | Kim, Y, Chhor, G, Endres, M, Babnigg, G, Schneewind, O, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-01-07 | 公開日 | 2022-01-19 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structure of the Pirin Family Protein Redox-sensitive Bicupin YhaK Bound to Copper Ion from Yersinia pestis To Be Published
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7QOR
| Structure of beta-lactamase TEM-171 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | 著者 | Hakanpaa, J, Petrova, T, Samygina, V.R, Chojnowski, G, Lamzin, V, Egorov, A.M. | 登録日 | 2021-12-28 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Crystal structures of the molecular class A beta-lactamase TEM-171 and its complexes with tazobactam. Acta Crystallogr D Struct Biol, 78, 2022
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8FWU
| Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
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6DMW
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8TA6
| Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain | 分子名称: | Chloride channel protein 2 | 著者 | Xu, M, Neelands, T, Powers, A.S, Liu, Y, Miller, S, Pintilie, G, Du Bois, J, Dror, R.O, Chiu, W, Maduke, M. | 登録日 | 2023-06-26 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | 主引用文献 | CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism. Elife, 12, 2024
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5J7F
| Structure of MDM2 with low molecular weight inhibitor with aliphatic linker. | 分子名称: | 4-({6-[(6-chloro-3-{1-[(4-chlorophenyl)methyl]-4-(4-fluorophenyl)-1H-imidazol-5-yl}-1H-indole-2-carbonyl)oxy]hexyl}amino)-4-oxobutanoic acid, E3 ubiquitin-protein ligase Mdm2 | 著者 | Twarda-Clapa, A, Kubica, K, Guzik, K, Dubin, G, Holak, T.A. | 登録日 | 2016-04-06 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers. J. Med. Chem., 60, 2017
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