5F5H

X-ray structure of Roquin ROQ domain in complex with Ox40 hexa-loop RNA motif

Summary for 5F5H

• Entry DOI: 10.2210/pdb5f5h/pdb
• Descriptor: Roquin-1, RNA (5'-R(P*CP*CP*AP*CP*AP*CP*CP*GP*UP*UP*CP*UP*AP*GP*GP*UP*GP*CP*UP*GP*G)-3'), GLYCEROL, ... (4 entities in total)
• Functional Keywords: roq domain, winged-helix domain, rna binding protein, ox40 mrna
• Biological source: Mus musculus (House mouse); More
• Cellular location: Cytoplasm, P-body : Q4VGL6
• Total number of polymer chains: 4
• Total formula weight: 55123.54

Authors

Janowski, R.,Schlundt, A.,Sattler, M.,Niessing, D. (deposition date: 2015-12-04, release date: 2016-04-06, Last modification date: 2024-01-10)

• Primary citation: Janowski, R.,Heinz, G.A.,Schlundt, A.,Wommelsdorf, N.,Brenner, S.,Gruber, A.R.,Blank, M.,Buch, T.,Buhmann, R.,Zavolan, M.,Niessing, D.,Heissmeyer, V.,Sattler, M.; Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.; Nat Commun, 7:11032-11032, 2016; PubMed: 27010430; DOI: 10.1038/ncomms11032

Experimental method

X-RAY DIFFRACTION (2.23 Å)