5ITH

TIA-1 RRM2 recognition of target oligonucleotide

Summary for 5ITH

• Entry DOI: 10.2210/pdb5ith/pdb
• Descriptor: Nucleolysin TIA-1 isoform p40, DNA (5'-D(*AP*CP*TP*CP*C*TP*TP*TP*TP*T)-3') (3 entities in total)
• Functional Keywords: rrm, rna/dna binding domain, poly u binding preference, aromatic base stacking interactions, dna binding protein-dna complex, rna binding protein-dna complex, rna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasmic granule : P31483
• Total number of polymer chains: 2
• Total formula weight: 13209.46

Authors

Waris, S.,Wilce, J.A.,Wilce, M.C. (deposition date: 2016-03-16, release date: 2017-02-22, Last modification date: 2023-09-27)

• Primary citation: Waris, S.,Garcia-Maurino, S.M.,Sivakumaran, A.,Beckham, S.A.,Loughlin, F.E.,Gorospe, M.,Diaz-Moreno, I.,Wilce, M.C.J.,Wilce, J.A.; TIA-1 RRM23 binding and recognition of target oligonucleotides.; Nucleic Acids Res., 45:4944-4957, 2017; PubMed: 28184449; DOI: 10.1093/nar/gkx102

Experimental method

X-RAY DIFFRACTION (2.31 Å)