8TA6

Cryo-EM structure of the human CLC-2 chloride channel C-terminal domain

Summary for 8TA6

• Entry DOI: 10.2210/pdb8ta6/pdb
• EMDB information: 41126 41127 41128 41129 41130
• Descriptor: Chloride channel protein 2 (1 entity in total)
• Functional Keywords: chloride, channel, inhibitor, protein, voltage gated, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 197284.70

Authors

Xu, M.,Neelands, T.,Powers, A.S.,Liu, Y.,Miller, S.,Pintilie, G.,Du Bois, J.,Dror, R.O.,Chiu, W.,Maduke, M. (deposition date: 2023-06-26, release date: 2024-01-31, Last modification date: 2024-02-28)

• Primary citation: Xu, M.,Neelands, T.,Powers, A.S.,Liu, Y.,Miller, S.D.,Pintilie, G.D.,Bois, J.D.,Dror, R.O.,Chiu, W.,Maduke, M.; CryoEM structures of the human CLC-2 voltage-gated chloride channel reveal a ball-and-chain gating mechanism.; Elife, 12:-, 2024; PubMed: 38345841; DOI: 10.7554/eLife.90648

Experimental method

ELECTRON MICROSCOPY (4.03 Å)