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PDB: 292 results

5FGG
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BU of 5fgg by Molmil
Yeast 20S proteasome beta5-L(-49S)_D17N double mutant in complex with Carfilzomib
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-12-20
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGD
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BU of 5fgd by Molmil
Yeast 20S proteasome beta5-H(-2)L-T1A double mutant in complex with Carfilzomib
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-12-20
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGI
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BU of 5fgi by Molmil
Yeast 20S proteasome beta1-T1A beta2-T1A double mutant in complex with Carfilzomib
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-12-20
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5FGH
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BU of 5fgh by Molmil
Yeast 20S proteasome beta5-K33A mutant (propeptide expressed in trans) in complex with MG132
Descriptor: CHLORIDE ION, MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-12-20
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
4Y81
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BU of 4y81 by Molmil
Yeast 20S proteasome in complex with Ac-PAY-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAY-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4YA2
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BU of 4ya2 by Molmil
Yeast 20S proteasome beta2-H116N mutant in complex with Ac-LAE-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAE-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-17
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8H
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BU of 4y8h by Molmil
Yeast 20S proteasome in complex with N3-APAL-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8Q
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BU of 4y8q by Molmil
Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAY-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAY-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y75
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BU of 4y75 by Molmil
Yeast 20S proteasome in complex with Ac-PAF-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAF-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-13
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8O
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BU of 4y8o by Molmil
Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAF-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PAF-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y77
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BU of 4y77 by Molmil
Yeast 20S proteasome in complex with Ac-LAF-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAF-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-13
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y69
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BU of 4y69 by Molmil
Yeast 20S proteasome in complex with Ac-PAD-ep
Descriptor: Ac-PAD-ep, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-12
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8N
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BU of 4y8n by Molmil
Yeast 20S proteasome beta7-delta7_Cter mutant in complex with Ac-PAE-ep
Descriptor: Ac-PAE-ep, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8T
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BU of 4y8t by Molmil
Yeast 20S proteasome beta2-H116D mutant in complex with Ac-PAE-ep
Descriptor: Ac-PAE-ep, MAGNESIUM ION, Proteasome subunit alpha type-1, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
7AW9
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BU of 7aw9 by Molmil
CCAAT-binding complex and HapX bound to Aspergillus fumigatus cccA DNA
Descriptor: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2020-11-06
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX.
Structure, 30, 2022
7AW7
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BU of 7aw7 by Molmil
CCAAT-binding complex and HapX bound to Aspergillus nidulans cccA DNA
Descriptor: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2020-11-06
Release date:2022-04-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX.
Structure, 30, 2022
7Q3Z
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BU of 7q3z by Molmil
DNA/RNA binding protein
Descriptor: SODIUM ION, Schlafen family member 5, ZINC ION
Authors:Huber, E, Lammens, K.
Deposit date:2021-10-29
Release date:2022-01-26
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and biochemical characterization of human Schlafen 5.
Nucleic Acids Res., 50, 2022
6RR9
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BU of 6rr9 by Molmil
DNA/RNA binding protein
Descriptor: GLYCEROL, SULFATE ION, Schlafen family member 5, ...
Authors:Huber, E, Lammens, K.
Deposit date:2019-05-17
Release date:2020-07-08
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (3.432 Å)
Cite:Structural and biochemical characterization of human Schlafen 5.
Nucleic Acids Res., 2022
5JHR
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BU of 5jhr by Molmil
Yeast 20S proteasome in complex with the peptidic epoxyketone inhibitor 27
Descriptor: (2S)-2-azido-N-[(2S)-3-(biphenyl-4-yl)-1-{[(2S)-1-{[(2S,3S,4R)-3,5-dihydroxy-4-methylpentan-2-yl]amino}-1-oxo-3-phenylpropan-2-yl]amino}-1-oxopropan-2-yl]-3-phenylpropanamide (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2016-04-21
Release date:2016-08-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of beta 5c Selective Inhibitors of Human Constitutive Proteasomes.
J.Med.Chem., 59, 2016
5MX5
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BU of 5mx5 by Molmil
Mouse PA28alpha-beta
Descriptor: PHOSPHATE ION, Proteasome activator complex subunit 1, Proteasome activator complex subunit 2
Authors:Huber, E.M, Groll, M.
Deposit date:2017-01-20
Release date:2017-09-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Mammalian Proteasome Activator PA28 Forms an Asymmetric alpha 4 beta 3 Complex.
Structure, 25, 2017
5MSJ
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BU of 5msj by Molmil
Mouse PA28alpha
Descriptor: Proteasome activator complex subunit 1
Authors:Huber, E.M, Groll, M.
Deposit date:2017-01-05
Release date:2017-09-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The Mammalian Proteasome Activator PA28 Forms an Asymmetric alpha 4 beta 3 Complex.
Structure, 25, 2017
5MSK
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BU of 5msk by Molmil
Mouse PA28beta
Descriptor: Proteasome activator complex subunit 2
Authors:Huber, E.M, Groll, M.
Deposit date:2017-01-05
Release date:2017-09-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The Mammalian Proteasome Activator PA28 Forms an Asymmetric alpha 4 beta 3 Complex.
Structure, 25, 2017
4Y7W
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BU of 4y7w by Molmil
Yeast 20S proteasome in complex with Ac-LAE-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAE-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4Y8J
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BU of 4y8j by Molmil
Yeast 20S proteasome in complex with Ac-LLL-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-PLL-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-16
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015
4YA7
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BU of 4ya7 by Molmil
Yeast 20S proteasome beta2-H114D mutant in complex with Ac-LAE-ep
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ac-LAE-ep, CHLORIDE ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-02-17
Release date:2015-06-17
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137, 2015

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