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4Y8J

Yeast 20S proteasome in complex with Ac-LLL-ep

Summary for 4Y8J
Entry DOI10.2210/pdb4y8j/pdb
Related1RYP
DescriptorProteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (19 entities in total)
Functional Keywordshydrolase-hydrolase inhibitor complex, proteasome, inhibitor, binding analysis, hydrolase/hydrolase inhibitor
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
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Cellular locationCytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451
Total number of polymer chains34
Total formula weight734648.85
Authors
Huber, E.M.,Groll, M. (deposition date: 2015-02-16, release date: 2015-06-17, Last modification date: 2024-01-10)
Primary citationHuber, E.M.,de Bruin, G.,Heinemeyer, W.,Paniagua Soriano, G.,Overkleeft, H.S.,Groll, M.
Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors.
J.Am.Chem.Soc., 137:7835-7842, 2015
Cited by
PubMed: 26020686
DOI: 10.1021/jacs.5b03688
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

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