8HJ4
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3ZIF
| Cryo-EM structures of two intermediates provide insight into adenovirus assembly and disassembly | Descriptor: | HEXON PROTEIN, PENTON PROTEIN, PIX, ... | Authors: | Cheng, L, Huang, X, Li, X, Xiong, W, Sun, W, Yang, C, Zhang, K, Wang, Y, Liu, H, Ji, G, Sun, F, Zheng, C, Zhu, P. | Deposit date: | 2013-01-09 | Release date: | 2014-01-22 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-Em Structures of Two Bovine Adenovirus Type 3 Intermediates Virology, 450, 2014
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6DRJ
| Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, ADPR/Ca2+ bound state | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel, ... | Authors: | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | Deposit date: | 2018-06-12 | Release date: | 2018-09-19 | Last modified: | 2018-10-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
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6DRK
| Structure of TRPM2 ion channel receptor by single particle electron cryo-microscopy, Apo state | Descriptor: | Transient receptor potential cation channel, subfamily M, member 2 | Authors: | Du, J, Lu, W, Huang, Y, Winkler, P, Sun, W. | Deposit date: | 2018-06-12 | Release date: | 2018-09-19 | Last modified: | 2018-10-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium. Nature, 562, 2018
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5WP6
| Cryo-EM structure of a human TRPM4 channel in complex with calcium and decavanadate | Descriptor: | DECAVANADATE, Transient receptor potential cation channel subfamily M member 4 | Authors: | Winkler, P.A, Huang, Y, Sun, W, Du, J, Lu, W. | Deposit date: | 2017-08-03 | Release date: | 2017-12-13 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Electron cryo-microscopy structure of a human TRPM4 channel. Nature, 552, 2017
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7BZ2
| Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex. | Descriptor: | Beta2 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Zhang, Y.N, Yang, F, Ling, S.L, Lv, P, Zhou, Y.X, Fang, W, Sun, W, Shi, P, Tian, C.L. | Deposit date: | 2020-04-26 | Release date: | 2020-08-05 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Single-particle cryo-EM structural studies of the beta2AR-Gs complex bound with a full agonist formoterol. Cell Discov, 6, 2020
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6JD7
| Crystal structure of anti-CRISPR protein AcrIIC2 dimer | Descriptor: | ACETATE ION, AcrIIC2, MAGNESIUM ION | Authors: | Cheng, Z, Huang, X, Sun, W, Wang, Y.L. | Deposit date: | 2019-01-31 | Release date: | 2019-05-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun, 10, 2019
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6JDX
| Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 preprocessed with protease alpha-Chymotrypsin | Descriptor: | 1,2-ETHANEDIOL, AcrIIC2, CRISPR-associated endonuclease Cas9 | Authors: | Cheng, Z, Huang, X, Sun, W, Wang, Y. | Deposit date: | 2019-02-02 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun, 10, 2019
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6JDJ
| Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9 | Descriptor: | AcrIIC2, CRISPR-associated endonuclease Cas9 | Authors: | Cheng, Z, Huang, X, Sun, W, Wang, Y. | Deposit date: | 2019-02-01 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun, 10, 2019
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6LTU
| Crystal structure of Cas12i2 ternary complex with double Mg2+ bound in catalytic pocket | Descriptor: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-23 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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6LTR
| Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket | Descriptor: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-23 | Release date: | 2020-10-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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6LU0
| Crystal structure of Cas12i2 ternary complex with 12 nt spacer | Descriptor: | Cas12i2, DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*T)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*CP*TP*CP*TP*GP*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*C)-3'), ... | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-24 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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6LTP
| Crystal structure of Cas12i2 binary complex | Descriptor: | Cas12i2, crRNA (56-mer RNA) | Authors: | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | Deposit date: | 2020-01-23 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
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8GW3
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8J0H
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7CZ5
| Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex | Descriptor: | CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | Deposit date: | 2020-09-07 | Release date: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural basis for activation of the growth hormone-releasing hormone receptor. Nat Commun, 11, 2020
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4WUM
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1GJQ
| Pseudomonas aeruginosa cd1 nitrite reductase reduced cyanide complex | Descriptor: | CYANIDE ION, HEME C, HEME D, ... | Authors: | Nurizzo, D, Brown, K, Tegoni, M, Cambillau, C. | Deposit date: | 2001-08-01 | Release date: | 2002-08-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cyanide Binding to Cd(1) Nitrite Reductase from Pseudomonas Aeruginosa: Role of the Active-Site His369 in Ligand Stabilization. Biochem.Biophys.Res.Commun., 291, 2002
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7L4S
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8JBH
| Substance P bound to active human neurokinin 3 receptor in complex with Gq | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein Gq subunit alpha (G324), ... | Authors: | Sun, W.J, Yang, F, Zhang, H.H, Yuan, Q.N, Yin, W.C, Shi, P, Eric, X, Tian, C.L. | Deposit date: | 2023-05-08 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists. Cell Discov, 9, 2023
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8JBG
| Neurokinin B bound to active human neurokinin 3 receptor in complex with Gq | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein Gq (G324), ... | Authors: | Sun, W.J, Yang, F, Zhang, H.H, Yuan, Q.N, Yin, W.C, Shi, P, Eric, X, Tian, C.L. | Deposit date: | 2023-05-08 | Release date: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists. Cell Discov, 9, 2023
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8JBF
| Senktide bound to active human neurokinin 3 receptor in complex with Gq | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein Gq subunit alpha, ... | Authors: | Sun, W.J, Yang, F, Zhang, H.H, Yuan, Q.N, Yin, W.C, Shi, P, Eric, X, Tian, C.L. | Deposit date: | 2023-05-08 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists. Cell Discov, 9, 2023
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7XWO
| Neurokinin A bound to active human neurokinin 2 receptor in complex with G324 | Descriptor: | G324, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Sun, W.J, Yuan, Q.N, Zhang, H.H, Yang, F, Ling, S.L, Lv, P, Eric, X, Tian, C.L, Yin, W.C, Shi, P. | Deposit date: | 2022-05-26 | Release date: | 2023-05-31 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the activation of neurokinin 2 receptor by neurokinin A. Cell Discov, 8, 2022
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6ZOV
| ENTEROPEPTIDASE IN COMPLEX WITH COMPOUND 6 | Descriptor: | 1,2-ETHANEDIOL, 4-GUANIDINOBENZOIC ACID, Enteropeptidase, ... | Authors: | Cummings, M.D. | Deposit date: | 2020-07-07 | Release date: | 2020-10-21 | Last modified: | 2020-12-09 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits. J.Pharmacol.Exp.Ther., 375, 2020
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7XIV
| Structural insight into the interactions between Lloviu virus VP30 and nucleoprotein | Descriptor: | Nucleocapsid protein,Minor nucleoprotein VP30 | Authors: | Dong, S.S, Qin, X.C, Sun, W.Y, Luan, F.C, Wang, J.J, Ma, L, Li, X.X, Yang, G.X, Hao, C.Y. | Deposit date: | 2022-04-14 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Structural insights into the interactions between lloviu virus VP30 and nucleoprotein. Biochem.Biophys.Res.Commun., 616, 2022
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