7XWO

Neurokinin A bound to active human neurokinin 2 receptor in complex with G324

Summary for 7XWO

Entry DOI	10.2210/pdb7xwo/pdb
EMDB information	33497
Descriptor	Soluble cytochrome b562,Substance-K receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, scFv, ... (6 entities in total)
Functional Keywords	tachykinin receptor 2, neurokinin a, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	6
Total formula weight	178363.82
Authors	Sun, W.J.,Yuan, Q.N.,Zhang, H.H.,Yang, F.,Ling, S.L.,Lv, P.,Eric, X.,Tian, C.L.,Yin, W.C.,Shi, P. (deposition date: 2022-05-26, release date: 2023-05-31, Last modification date: 2023-12-13)
Primary citation	Sun, W.,Yuan, Q.,Zhang, H.,Yang, F.,Ling, S.,Luo, Y.,Lv, P.,Eric Xu, H.,Tian, C.,Yin, W.,Shi, P. Structural insights into the activation of neurokinin 2 receptor by neurokinin A. Cell Discov, 8:72-72, 2022 Cited by PubMed: 35882833 DOI: 10.1038/s41421-022-00437-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation