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7BZ2

Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex.

Summary for 7BZ2
Entry DOI10.2210/pdb7bz2/pdb
EMDB information30249
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywordsreceptor, formoterol, complex, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains5
Total formula weight151803.50
Authors
Zhang, Y.N.,Yang, F.,Ling, S.L.,Lv, P.,Zhou, Y.X.,Fang, W.,Sun, W.,Shi, P.,Tian, C.L. (deposition date: 2020-04-26, release date: 2020-08-05)
Primary citationZhang, Y.,Yang, F.,Ling, S.,Lv, P.,Zhou, Y.,Fang, W.,Sun, W.,Zhang, L.,Shi, P.,Tian, C.
Single-particle cryo-EM structural studies of the beta2AR-Gs complex bound with a full agonist formoterol.
Cell Discov, 6:45-45, 2020
Cited by
PubMed: 32655881
DOI: 10.1038/s41421-020-0176-9
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.82 Å)
Structure validation

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