8JBF
Senktide bound to active human neurokinin 3 receptor in complex with Gq
Summary for 8JBF
Entry DOI | 10.2210/pdb8jbf/pdb |
EMDB information | 36144 |
Descriptor | Neuromedin-K receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16 nanobody, ... (6 entities in total) |
Functional Keywords | g protein coupled receptor, neurokinin, cryo-em, peptide agonists, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 168538.77 |
Authors | Sun, W.J.,Yang, F.,Zhang, H.H.,Yuan, Q.N.,Yin, W.C.,Shi, P.,Eric, X.,Tian, C.L. (deposition date: 2023-05-08, release date: 2024-02-28) |
Primary citation | Sun, W.,Yang, F.,Zhang, H.,Yuan, Q.,Ling, S.,Wang, Y.,Lv, P.,Li, Z.,Luo, Y.,Liu, D.,Yin, W.,Shi, P.,Xu, H.E.,Tian, C. Structural insights into neurokinin 3 receptor activation by endogenous and analogue peptide agonists. Cell Discov, 9:66-66, 2023 Cited by PubMed: 37391393DOI: 10.1038/s41421-023-00564-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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