5WP6

Cryo-EM structure of a human TRPM4 channel in complex with calcium and decavanadate

Summary for 5WP6

Entry DOI	10.2210/pdb5wp6/pdb
EMDB information	8871 8872 8875 8876 8877 8878 8879
Descriptor	Transient receptor potential cation channel subfamily M member 4, DECAVANADATE (2 entities in total)
Functional Keywords	ion channel, membrane protein
Biological source	Homo sapiens (Human)
Cellular location	Isoform 1: Cell membrane; Multi-pass membrane protein. Isoform 2: Endoplasmic reticulum: Q8TD43
Total number of polymer chains	4
Total formula weight	545485.12
Authors	Winkler, P.A.,Huang, Y.,Sun, W.,Du, J.,Lu, W. (deposition date: 2017-08-03, release date: 2017-12-13, Last modification date: 2023-03-29)
Primary citation	Winkler, P.A.,Huang, Y.,Sun, W.,Du, J.,Lu, W. Electron cryo-microscopy structure of a human TRPM4 channel. Nature, 552:200-204, 2017 Cited by PubMed: 29211723 DOI: 10.1038/nature24674 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation