7XIE
| Crystal structure of a dimeric interlocked parallel G-quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION | Authors: | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | Deposit date: | 2022-04-13 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex. Biochem.Biophys.Res.Commun., 613, 2022
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7XH9
| Crystal structure of a dimeric interlocked parallel G-quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*CP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION, STRONTIUM ION | Authors: | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | Deposit date: | 2022-04-07 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A.G.G.G.G pentad in an interlocked G-quadruplex. Biochem.Biophys.Res.Commun., 613, 2022
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7XHD
| Crystal structure of a dimeric interlocked parallel G-quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION | Authors: | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | Deposit date: | 2022-04-08 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex. Biochem.Biophys.Res.Commun., 613, 2022
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6JCE
| NMR solution and X-ray crystal structures of a DNA containing both right-and left-handed parallel-stranded G-quadruplexes | Descriptor: | 29-mer DNA | Authors: | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Mechulam, Y, Schmitt, E, Phan, A.T. | Deposit date: | 2019-01-28 | Release date: | 2019-07-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., 47, 2019
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6JCD
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6K3X
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6K3Y
| G-quadruplex complex with cyclic dinucleotide 3'-3' cGAMP | Descriptor: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, DNA (5'-D(*TP*TP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | Authors: | Winnerdy, F.R, Heddi, B, Phan, A.T. | Deposit date: | 2019-05-22 | Release date: | 2020-01-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution Structures of a G-Quadruplex Bound to Linear- and Cyclic-Dinucleotides. J.Am.Chem.Soc., 141, 2019
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6L92
| A basket type G-quadruplex in WNT DNA promoter | Descriptor: | DNA (5'-D(*GP*GP*GP*CP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3') | Authors: | Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C. | Deposit date: | 2019-11-08 | Release date: | 2019-12-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter. Nucleic Acids Res., 48, 2020
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6KVB
| Structure of an intra-locked G-quadruplex | Descriptor: | DNA (28-mer) | Authors: | Maity, A, Winnerdy, F.R, Chang, W.D, Chen, G, Phan, A.T. | Deposit date: | 2019-09-03 | Release date: | 2020-03-04 | Last modified: | 2020-04-15 | Method: | SOLUTION NMR | Cite: | Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs. Nucleic Acids Res., 48, 2020
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6L8M
| WNT DNA promoter mutant G-quadruplex | Descriptor: | DNA (5'-D(*GP*GP*GP*TP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3') | Authors: | Wang, Z.F, Li, M.H, Chu, I.T, Winnerdy, F.R, Phan, A.T, Chang, T.C. | Deposit date: | 2019-11-06 | Release date: | 2019-12-11 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter. Nucleic Acids Res., 48, 2020
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7VF1
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1YKV
| Crystal structure of the Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene | Descriptor: | (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, Diels-Alder ribozyme, MAGNESIUM ION | Authors: | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | Deposit date: | 2005-01-18 | Release date: | 2005-02-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
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1YKQ
| Crystal structure of Diels-Alder ribozyme | Descriptor: | CADMIUM ION, Diels-Alder ribozyme, MAGNESIUM ION | Authors: | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | Deposit date: | 2005-01-18 | Release date: | 2005-02-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
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1YLS
| Crystal structure of selenium-modified Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene | Descriptor: | (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION, RNA Diels-Alder ribozyme | Authors: | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | Deposit date: | 2005-01-19 | Release date: | 2005-02-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
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1YTY
| Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen | Descriptor: | 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein | Authors: | Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J. | Deposit date: | 2005-02-11 | Release date: | 2006-01-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell, 21, 2006
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1ZH5
| Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen | Descriptor: | 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein, SULFATE ION | Authors: | Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J. | Deposit date: | 2005-04-22 | Release date: | 2006-01-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen. Mol.Cell, 21, 2006
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2AQY
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6AC7
| Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter | Descriptor: | 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*GP*AP*GP*GP*CP*GP*GP*GP*GP*CP*TP*TP*GP*GP*G)-3' | Authors: | Sengar, A, Vandana, J.J, Chambers, V.S, Di Antonio, M, Winnerdy, F.R, Balasubramanian, S, Phan, A.T. | Deposit date: | 2018-07-25 | Release date: | 2019-02-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter. Nucleic Acids Res., 47, 2019
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7EUC
| Parallel G-quadruplex structure | Descriptor: | DNA (5'-D(*TP*TP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*GP*GP*T)-3'), ... | Authors: | Winnerdy, F.R, Devi, G, Ang, J.C.Y, Lim, K.W, Phan, A.T. | Deposit date: | 2021-05-17 | Release date: | 2022-03-30 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Four-Layered Intramolecular Parallel G-Quadruplex with Non-Nucleotide Loops: An Ultra-Stable Self-Folded DNA Nano-Scaffold. Acs Nano, 16, 2022
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6FQ2
| Structure of minimal sequence for left -handed G-quadruplex formation | Descriptor: | DNA (5'-D(*GP*TP*GP*GP*TP*GP*GP*TP*GP*GP*TP*G)-3'), POTASSIUM ION | Authors: | Schmitt, E, Mechulam, Y, Phan, A.T, Heddi, B, Bakalar, B. | Deposit date: | 2018-02-13 | Release date: | 2018-12-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew. Chem. Int. Ed. Engl., 58, 2019
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6GZ6
| Structure of a left-handed G-quadruplex | Descriptor: | DNA (27-MER), POTASSIUM ION | Authors: | Bakalar, B, Heddi, B, Schmitt, E, Mechulam, Y, Phan, A.T. | Deposit date: | 2018-07-03 | Release date: | 2019-04-24 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.006 Å) | Cite: | A Minimal Sequence for Left-Handed G-Quadruplex Formation. Angew.Chem.Int.Ed.Engl., 58, 2019
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2LK7
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2LE6
| Structure of a dimeric all-parallel-stranded G-quadruplex stacked via the 5'-to-5' interface | Descriptor: | DNA (5'-D(*GP*IP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*T)-3') | Authors: | Do, N.Q, Lim, K.W, Teo, M.H, Heddi, B, Phan, A.T. | Deposit date: | 2011-06-10 | Release date: | 2011-08-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activity Nucleic Acids Res., 2011
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2MB2
| parallel-stranded G-quadruplex in DNA poly-G stretches | Descriptor: | DNA_(5'-D(*TP*TP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*GP*T)-3') | Authors: | Sengar, A, Heddi, B, Phan, A.T. | Deposit date: | 2013-07-24 | Release date: | 2014-12-03 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Formation of g-quadruplexes in poly-g sequences: structure of a propeller-type parallel-stranded g-quadruplex formed by a g15 stretch. Biochemistry, 53, 2014
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2M90
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