1XKA
| |
2MJP
| STRUCTURE-BASED IDENTIFICATION OF THE BIOCHEMICAL FUNCTION OF A HYPOTHETICAL PROTEIN FROM METHANOCOCCUS JANNASCHII:MJ0226 | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PYROPHOSPHATASE | Authors: | Hwang, K.Y, Chung, J.H, Han, Y.S, Kim, S.H, Cho, Y, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 1999-01-27 | Release date: | 2000-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based identification of a novel NTPase from Methanococcus jannaschii. Nat.Struct.Biol., 6, 1999
|
|
6ICJ
| Crystal structure of PPARgamma with compound BR102375K | Descriptor: | 2-butyl-5-[(3-tert-butyl-1,2,4-oxadiazol-5-yl)methyl]-6-methyl-3-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}pyrimidin-4(3H)-one, GLYCEROL, Nuclear receptor coactivator 1, ... | Authors: | Hong, E, Chin, J, Jang, T.H, Kim, K.H, Jung, W, Kim, S.H. | Deposit date: | 2018-09-06 | Release date: | 2019-09-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.483 Å) | Cite: | Crystal structure of PPARgamma with compound BR102375K To Be Published
|
|
1PF8
| Crystal Structure of Human Cyclin-Dependent Kinase 2 Complexed with a Nucleoside Inhibitor | Descriptor: | (3Z)-3-(1H-IMIDAZOL-5-YLMETHYLENE)-5-METHOXY-1H-INDOL-2(3H)-ONE, Cell division protein kinase 2 | Authors: | Moshinsky, D.J, Bellamacina, R.C, Boisvert, D.C, Huang, P, Hui, T, Jancarik, J, Kim, S.H, Rice, A.G. | Deposit date: | 2003-05-24 | Release date: | 2003-12-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2. Biochem.Biophys.Res.Commun., 310, 2003
|
|
1KRL
| Crystal Structure of Racemic DL-monellin in P-1 | Descriptor: | MONELLIN, CHAIN A, CHAIN B | Authors: | Hung, L.W, Kohmura, M, Ariyoshi, Y, Kim, S.H. | Deposit date: | 2002-01-10 | Release date: | 2002-02-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural differences in D and L-monellin in the crystals of racemic mixture. J.Mol.Biol., 285, 1999
|
|
1THI
| |
3MON
| |
6KIA
| |
6KI9
| Apo structure of FabMG, novel types of Enoyl-acyl carrier protein reductase | Descriptor: | 1,2-ETHANEDIOL, FabMG, novel types of Enoyl-acyl carrier protein reductase, ... | Authors: | Kim, S, Rhee, S. | Deposit date: | 2019-07-17 | Release date: | 2020-05-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | A triclosan-resistance protein from the soil metagenome is a novel enoyl-acyl carrier protein reductase: Structure-guided functional analysis. Febs J., 287, 2020
|
|
3D5M
| Crystal structure of HCV NS5B polymerase with a novel pyridazinone inhibitor | Descriptor: | N-({3-[(5S)-5-tert-butyl-1-(3-chloro-4-fluorobenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-1,2-benzis othiazol-7-yl}methyl)methanesulfonamide, RNA-directed RNA polymerase | Authors: | Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R. | Deposit date: | 2008-05-16 | Release date: | 2009-05-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg.Med.Chem.Lett., 18, 2008
|
|
3D28
| Crystal structure of hcv ns5b polymerase with a novel benzisothiazole inhibitor | Descriptor: | (5S)-1-benzyl-3-(1,1-dioxido-1,2-benzisothiazol-3-yl)-4-hydroxy-5-(1-methylethyl)-1,5-dihydro-2H-pyrrol-2-one, RNA-directed RNA polymerase | Authors: | Han, Q, Showalter, R.E, Zhao, Q, Kissinger, C.R. | Deposit date: | 2008-05-07 | Release date: | 2009-05-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-based design, synthesis, and biological evaluation of 1,1-dioxoisothiazole and benzo[b]thiophene-1,1-dioxide derivatives as novel inhibitors of hepatitis C virus NS5B polymerase. Bioorg.Med.Chem.Lett., 18, 2008
|
|
4KNW
| |
4KNV
| The crystal structure of APO HUMAN HDHD4 FROM SE-MAD | Descriptor: | MAGNESIUM ION, N-acylneuraminate-9-phosphatase, PHOSPHATE ION | Authors: | Klei, H.E. | Deposit date: | 2013-05-10 | Release date: | 2013-06-26 | Last modified: | 2013-07-10 | Method: | X-RAY DIFFRACTION (1.993 Å) | Cite: | Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex. Bioorg.Med.Chem.Lett., 23, 2013
|
|
4UV7
| The complex structure of extracellular domain of EGFR and GC1118A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EPIDERMAL GROWTH FACTOR RECEPTOR, ... | Authors: | Yoo, J.H, Cho, H.S. | Deposit date: | 2014-08-05 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Gc1118, an Anti-Egfr Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity Against High-Affinity Egfr Ligands. Mol.Cancer Ther., 15, 2016
|
|
6TNA
| CRYSTAL STRUCTURE OF YEAST PHENYLALANINE T-RNA. I.CRYSTALLOGRAPHIC REFINEMENT | Descriptor: | MAGNESIUM ION, TRNAPHE | Authors: | Sussman, J.L, Holbrook, S.R, Warrant, R.W, Church, G.M, Kim, S.-H. | Deposit date: | 1978-11-16 | Release date: | 1979-01-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement. J.Mol.Biol., 123, 1978
|
|
1B8P
| MALATE DEHYDROGENASE FROM AQUASPIRILLUM ARCTICUM | Descriptor: | PROTEIN (MALATE DEHYDROGENASE) | Authors: | Kim, S.Y, Hwang, K.Y, Kim, S.-H, Han, Y.S, Cho, Y. | Deposit date: | 1999-02-02 | Release date: | 1999-07-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J.Biol.Chem., 274, 1999
|
|
1BCC
| CYTOCHROME BC1 COMPLEX FROM CHICKEN | Descriptor: | 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.-I, Kim, K.K, Hung, L.-W, Crofts, A.R, Berry, E.A, Kim, S.-H. | Deposit date: | 1998-03-23 | Release date: | 1998-08-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Electron transfer by domain movement in cytochrome bc1. Nature, 392, 1998
|
|
1BU2
| |
1B8U
| MALATE DEHYDROGENASE FROM AQUASPIRILLUM ARCTICUM | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALOACETATE ION, PROTEIN (MALATE DEHYDROGENASE) | Authors: | Kim, S.Y, Hwang, K.Y, Kim, S.-H, Han, Y.S, Cho, Y. | Deposit date: | 1999-02-02 | Release date: | 1999-07-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J.Biol.Chem., 274, 1999
|
|
4EDA
| Structures of monomeric hemagglutinin and its complex with an Fab fragment of a neutralizing antibody that binds to H1 subtype influenza viruses: molecular basis of infectivity of 2009 pandemic H1N1 influenza A viruses | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Kim, K.H, Cho, K.J, Lee, J.H, Park, Y.H, Khan, T.G, Lee, J.Y, Kang, S.H, Alam, I. | Deposit date: | 2012-03-27 | Release date: | 2013-05-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Insight into structural diversity of influenza virus haemagglutinin J.Gen.Virol., 94, 2013
|
|
8GTM
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL | Descriptor: | 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | Authors: | Cho, H.S, Kim, H. | Deposit date: | 2022-09-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
|
|
8GTG
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-I-152 by XFEL | Descriptor: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N},~{N}-bis(2-methoxyethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | Authors: | Cho, H.S, Kim, H. | Deposit date: | 2022-09-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
|
|
8GTI
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL | Descriptor: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, ... | Authors: | Cho, H.S, Kim, H. | Deposit date: | 2022-09-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
|
|
2UZ8
| The crystal structure of p18, human translation elongation factor 1 epsilon 1 | Descriptor: | EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, GLYCEROL | Authors: | Kang, B.S, Kim, K.J, Kim, M.H, Oh, Y.S, Kim, S. | Deposit date: | 2007-04-26 | Release date: | 2008-03-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Determination of Three-Dimensional Structure and Residues of the Novel Tumor Suppressor Aimp3/P18 Required for the Interaction with Atm. J.Biol.Chem., 283, 2008
|
|
2G97
| |