8GTI

Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL

Summary for 8GTI

Entry DOI	10.2210/pdb8gti/pdb
Descriptor	Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, Endolysin, OLEIC ACID, ... (4 entities in total)
Functional Keywords	membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	52699.78
Authors	Cho, H.S.,Kim, H. (deposition date: 2022-09-08, release date: 2023-09-13, Last modification date: 2023-10-18)
Primary citation	Kim, H.,Lim, T.,Ha, G.E.,Lee, J.Y.,Kim, J.W.,Chang, N.,Kim, S.H.,Kim, K.H.,Lee, J.,Cho, Y.,Kim, B.W.,Abrahamsson, A.,Kim, S.H.,Kim, H.J.,Park, S.,Lee, S.J.,Park, J.,Cheong, E.,Kim, B.M.,Cho, H.S. Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55:2039-2050, 2023 Cited by PubMed: 37653040 DOI: 10.1038/s12276-023-01082-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation