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7XV6
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BU of 7xv6 by Molmil
Crystal structure of the Human TR4 DNA-Binding Domain with C-terminal extension (DBD-CTE) Homodimer Bound to DR1 Response Element
Descriptor: DNA (5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*GP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP*A)-3'), NR2C2 protein, ...
Authors:Liu, Y, Chen, Z.
Deposit date:2022-05-21
Release date:2022-12-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation.
Nucleic Acids Res., 51, 2023
7XT1
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BU of 7xt1 by Molmil
Crystal structure of Bypass-of-forespore protein C from Bacillus Subtilis
Descriptor: Protein BofC
Authors:Zhang, X.Y, Jiang, L.G, Huang, M.D.
Deposit date:2022-05-15
Release date:2023-05-17
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural Studies of Bypass of Forespore Protein C from Bacillus Subtilis to Reveal Its Inhibitory Molecular Mechanism for SpoIVB
Catalysts, 12, 2022
4I5N
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BU of 4i5n by Molmil
Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation
Descriptor: CALCIUM ION, MANGANESE (II) ION, Microcystin-LR (MCLR) bound form, ...
Authors:Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y.
Deposit date:2012-11-28
Release date:2013-05-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
4I5J
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BU of 4i5j by Molmil
PP2A PR70 Holoenzyme
Descriptor: CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Authors:Xing, Y, Jeffery, P.D, Shi, Y.
Deposit date:2012-11-28
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.091 Å)
Cite:Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
4I5K
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BU of 4i5k by Molmil
PP2A PR70 Holoenzyme model3_diCa_rcsb.pdb bppnat5_extend.mtz
Descriptor: CALCIUM ION, Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha
Authors:Xing, Y, Jeffrey, P.D, Shi, Y.
Deposit date:2012-11-28
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
4I5L
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BU of 4i5l by Molmil
Structural mechanism of trimeric PP2A holoenzyme involving PR70: insight for Cdc6 dephosphorylation
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, MALONATE ION, ...
Authors:Wlodarchak, N, Satyshur, K.A, Guo, F, Xing, Y.
Deposit date:2012-11-28
Release date:2013-05-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Structure of the Ca(2+)-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.
Cell Res., 23, 2013
7VM5
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BU of 7vm5 by Molmil
Crystal structure of uPA in complex with 4-guanidinobenzoic acid
Descriptor: 4-carbamimidamidobenzoic acid, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator
Authors:Jiang, L.G, Huang, M.D.
Deposit date:2021-10-07
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7VM4
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BU of 7vm4 by Molmil
Crystal structure of uPA in complex with nafamostat
Descriptor: 4-carbamimidamidobenzoic acid, TRIETHYLENE GLYCOL, Urokinase-type plasminogen activator
Authors:Jiang, L.G, Huang, M.D.
Deposit date:2021-10-07
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7VM6
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BU of 7vm6 by Molmil
Crystal structure of uPA in complex with 6-amidino-2-naphthol
Descriptor: 6-oxidanylnaphthalene-2-carboximidamide, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Jiang, L.G, Huang, M.D.
Deposit date:2021-10-07
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7VM7
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BU of 7vm7 by Molmil
Crystal structure of inactive uPA in complex with nafamostat
Descriptor: (6-carbamimidoylnaphthalen-2-yl) 4-carbamimidamidobenzoate, Urokinase-type plasminogen activator chain B
Authors:Jiang, L.G, Huang, M.D.
Deposit date:2021-10-07
Release date:2022-11-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural study of the uPA-nafamostat complex reveals a covalent inhibitory mechanism of nafamostat.
Biophys.J., 121, 2022
7WF5
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BU of 7wf5 by Molmil
c-Src in complex with ponatinib
Descriptor: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, Proto-oncogene tyrosine-protein kinase Src
Authors:Guo, M, Duan, Y, Dai, S, Chen, X, Chen, Y.
Deposit date:2021-12-26
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Structural study of ponatinib in inhibiting SRC kinase.
Biochem.Biophys.Res.Commun., 598, 2022
7WZ6
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BU of 7wz6 by Molmil
Crystal structure of MyoD-E47
Descriptor: Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1
Authors:Zhong, J, Huang, Y, Ma, J.
Deposit date:2022-02-17
Release date:2022-06-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis of the bHLH domains of MyoD-E47 heterodimer.
Biochem.Biophys.Res.Commun., 621, 2022
7X4W
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BU of 7x4w by Molmil
Crystal structure of Keap1 BTB domain in complex with dimethyl fumarate (DMF)
Descriptor: Dimethyl fumarate, Kelch-like ECH-associated protein 1
Authors:Qu, L.Z.
Deposit date:2022-03-03
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.209 Å)
Cite:Characterization of the modification of Kelch-like ECH-associated protein 1 by different fumarates.
Biochem.Biophys.Res.Commun., 605, 2022
7X4X
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BU of 7x4x by Molmil
BTB domain of KEAP1 in complex with MEF
Descriptor: 4-ethoxy-4-oxobutanoic acid, Kelch-like ECH-associated protein 1
Authors:Qu, L.Z.
Deposit date:2022-03-03
Release date:2023-03-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Characterization of the modification of Kelch-like ECH-associated protein 1 by different fumarates.
Biochem.Biophys.Res.Commun., 605, 2022
7XDY
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BU of 7xdy by Molmil
Crystal structure of a receptor like kinase from Arabidopsis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Receptor-like protein kinase FERONIA
Authors:Kong, Y.Q, Ming, Z.H.
Deposit date:2022-03-29
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Structural and biochemical basis of Arabidopsis FERONIA receptor kinase-mediated early signaling initiation.
Plant Commun., 4, 2023
7XDW
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BU of 7xdw by Molmil
Crystal structure of a receptor like kinase from Arabidopsis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Receptor-like protein kinase FERONIA
Authors:Kong, Y.Q, Ming, Z.H.
Deposit date:2022-03-29
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.926 Å)
Cite:Structural and biochemical basis of Arabidopsis FERONIA receptor kinase-mediated early signaling initiation.
Plant Commun., 4, 2023
7XDV
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BU of 7xdv by Molmil
Crystal structure of a receptor like kinase from Arabidopsis
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Receptor-like protein kinase FERONIA
Authors:Kong, Y.Q, Ming, Z.H.
Deposit date:2022-03-29
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural and biochemical basis of Arabidopsis FERONIA receptor kinase-mediated early signaling initiation.
Plant Commun., 4, 2023
7XDX
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BU of 7xdx by Molmil
Crystal structure of a receptor like kinase from Arabidopsis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Receptor-like protein kinase FERONIA
Authors:Kong, Y.Q, Ming, Z.H.
Deposit date:2022-03-29
Release date:2023-03-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Structural and biochemical basis of Arabidopsis FERONIA receptor kinase-mediated early signaling initiation.
Plant Commun., 4, 2023
7YHN
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BU of 7yhn by Molmil
ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Du, T, Ji, M, Hou, Z, Lin, S, Zhang, J, Wu, D, Zhang, K, Lu, D, Xu, H, Chen, X.
Deposit date:2022-07-14
Release date:2023-07-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site.
J.Med.Chem., 65, 2022
7F2D
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BU of 7f2d by Molmil
Arabidopsis thaliana protease-associated domain of vacuolar-sorting receptor 1 in complex with cruciferin 1 C-terminal pentapeptide RVAAA (pH9)
Descriptor: Cruciferin 1 C-terminal peptide, Vacuolar-sorting receptor 1
Authors:Lui, S.N, Wong, K.B.
Deposit date:2021-06-10
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural insights into how vacuolar sorting receptors recognize the sorting determinants of seed storage proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
7F2I
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BU of 7f2i by Molmil
Arabidopsis thaliana protease-associated domain of vacuolar-sorting receptor 1 in complex with cruciferin 1 C-terminal pentapeptide RVAAA (pH6.5)
Descriptor: Cruciferin 1 C-terminal peptide, Vacuolar-sorting receptor 1
Authors:Lui, S.N, Wong, K.B.
Deposit date:2021-06-11
Release date:2022-01-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into how vacuolar sorting receptors recognize the sorting determinants of seed storage proteins.
Proc.Natl.Acad.Sci.USA, 119, 2022
6C3G
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BU of 6c3g by Molmil
AMYLOID FORMING PEPTIDE KALGIS FROM TRANSTHYRETIN
Descriptor: GLYCEROL, LYS-ALA-LEU-GLY-ILE-SER, SULFATE ION
Authors:Saelices, L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C3F
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BU of 6c3f by Molmil
AMYLOID FORMING PEPTIDE IYKVEI FROM TRANSTHYRETIN
Descriptor: ILE-TYR-LYS-VAL-GLU-ILE, trifluoroacetic acid
Authors:Saelices, L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-01-09
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
6C88
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BU of 6c88 by Molmil
STRUCTURE OF THE AMYLOID FORMING PEPTIDE VAVHVF FROM TRANSTHYRETIN
Descriptor: GLYCEROL, VAL-ALA-VAL-HIS-VAL-PHE
Authors:Saelices, L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-01-24
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Crystal structures of amyloidogenic segments of human transthyretin.
Protein Sci., 27, 2018
7BZW
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BU of 7bzw by Molmil
Structure of Hsp21
Descriptor: Heat shock protein 21, chloroplastic
Authors:Lau, W.C.Y.
Deposit date:2020-04-28
Release date:2021-04-28
Last modified:2021-10-13
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis of substrate recognition and thermal protection by a small heat shock protein.
Nat Commun, 12, 2021

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