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7X4W

Crystal structure of Keap1 BTB domain in complex with dimethyl fumarate (DMF)

Summary for 7X4W
Entry DOI10.2210/pdb7x4w/pdb
DescriptorKelch-like ECH-associated protein 1, Dimethyl fumarate (2 entities in total)
Functional Keywordskeap1, btb domain, signaling protein
Biological sourceHomo sapiens (human)
Total number of polymer chains6
Total formula weight93497.49
Authors
Qu, L.Z. (deposition date: 2022-03-03, release date: 2023-03-08, Last modification date: 2023-11-29)
Primary citationQu, L.,Guo, M.,Zhang, H.,Chen, X.,Wei, H.,Jiang, L.,Li, J.,Chen, Z.,Dai, S.,Chen, Y.
Characterization of the modification of Kelch-like ECH-associated protein 1 by different fumarates.
Biochem.Biophys.Res.Commun., 605:9-15, 2022
Cited by
PubMed: 35306364
DOI: 10.1016/j.bbrc.2022.03.059
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.209 Å)
Structure validation

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