7X4W
Crystal structure of Keap1 BTB domain in complex with dimethyl fumarate (DMF)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, D, E, F... | Kelch-like ECH-associated protein 1 | polymer | 139 | 15509.8 | 6 | UniProt (Q14145) Pfam (PF00651) In PDB | Homo sapiens (human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
2 | A, D, B | Dimethyl fumarate | non-polymer | 146.1 | 3 | Chemie (9HB) |
Sequence modifications
A, C, D, E, F, B: 48 - 180 (UniProt: Q14145)
PDB | External Database | Details |
---|---|---|
Ser 42 | - | expression tag |
Glu 43 | - | expression tag |
Gly 44 | - | expression tag |
Ser 45 | - | expression tag |
His 46 | - | expression tag |
Met 47 | - | expression tag |
Ala 172 | Ser 172 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 93059.1 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 438.4 | |
All* | Total formula weight | 93497.5 |