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3MOM
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Structure of holo HasAp H32A mutant complexed with imidazole from Pseudomonas aeruginosa to 2.25A Resolution
分子名称: Heme acquisition protein HasAp, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE
著者Lovell, S, Battaile, K.P, Jepkorir, G, Rodriguez, J.C, Rui, H, Im, W, Alontaga, A.Y, Yukl, E, Moenne-Loccoz, P, Rivera, M.
登録日2010-04-22
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural, NMR Spectroscopic, and Computational Investigation of Hemin Loading in the Hemophore HasAp from Pseudomonas aeruginosa.
J.Am.Chem.Soc., 132, 2010
3MOK
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Structure of Apo HasAp from Pseudomonas aeruginosa to 1.55A Resolution
分子名称: Heme acquisition protein HasAp, PHOSPHATE ION, SODIUM ION
著者Lovell, S, Battaile, K.P, Jepkorir, G, Rodriguez, J.C, Rui, H, Im, W, Alontaga, A.Y, Yukl, E, Moenne-Loccoz, P, Rivera, M.
登録日2010-04-22
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural, NMR Spectroscopic, and Computational Investigation of Hemin Loading in the Hemophore HasAp from Pseudomonas aeruginosa.
J.Am.Chem.Soc., 132, 2010
3MOL
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BU of 3mol by Molmil
Structure of dimeric holo HasAp H32A Mutant from Pseudomonas aeruginosa to 1.20A Resolution
分子名称: Heme acquisition protein HasAp, PROTOPORPHYRIN IX CONTAINING FE
著者Lovell, S, Battaile, K.P, Jepkorir, G, Rodriguez, J.C, Rui, H, Im, W, Alontaga, A.Y, Yukl, E, Moenne-Loccoz, P, Rivera, M.
登録日2010-04-22
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural, NMR Spectroscopic, and Computational Investigation of Hemin Loading in the Hemophore HasAp from Pseudomonas aeruginosa.
J.Am.Chem.Soc., 132, 2010
8E4O
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BU of 8e4o by Molmil
The closed C1-state mouse TRPM8 structure in complex with putative PI(4,5)P2
分子名称: Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y.
登録日2022-08-18
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2.
Science, 378, 2022
8E4N
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The closed C1-state mouse TRPM8 structure in complex with PI(4,5)P2
分子名称: Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y.
登録日2022-08-18
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2.
Science, 378, 2022
8E4L
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The open state mouse TRPM8 structure in complex with the cooling agonist C3, AITC, and PI(4,5)P2
分子名称: 3-isothiocyanatoprop-1-ene, CALCIUM ION, Transient receptor potential cation channel subfamily M member 8, ...
著者Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y.
登録日2022-08-18
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2.
Science, 378, 2022
8E4Q
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The closed C0-state flycatcher TRPM8 structure in complex with PI(4,5)P2
分子名称: Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y.
登録日2022-08-18
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2.
Science, 378, 2022
8E4M
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The intermediate C2-state mouse TRPM8 structure in complex with the cooling agonist C3 and PI(4,5)P2
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 8, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, ...
著者Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y.
登録日2022-08-18
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2.
Science, 378, 2022
8E4P
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BU of 8e4p by Molmil
Mouse TRPM8 structure determined in the ligand- and PI(4,5)P2-free condition, Class I , C0 state
分子名称: CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 8
著者Yin, Y, Zhang, F, Feng, S, Butay, K.J, Borgnia, M.J, Im, W, Lee, S.-Y.
登録日2022-08-18
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP 2.
Science, 378, 2022
8ET7
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Cryo-EM structure of the organic cation transporter 1 in complex with diphenhydramine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8ET8
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Cryo-EM structure of the organic cation transporter 1 in complex with verapamil
分子名称: (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8ET9
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BU of 8et9 by Molmil
Cryo-EM structure of the organic cation transporter 2 in complex with 1-methyl-4-phenylpyridinium
分子名称: 1-methyl-4-phenylpyridin-1-ium, OCT2
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
8ET6
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BU of 8et6 by Molmil
Cryo-EM structure of the organic cation transporter 1 in the apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, OCT1
著者Suo, Y, Wright, N.J, Lee, S.-Y.
登録日2022-10-16
公開日2023-05-31
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2.
Nat.Struct.Mol.Biol., 30, 2023
6X7I
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BU of 6x7i by Molmil
Structure of the C-terminal domain of BCL-XL in membrane
分子名称: Bcl-2-like protein 1
著者Yao, Y, Tian, Y, Marassi, F.M.
登録日2020-05-30
公開日2020-07-01
最終更新日2023-06-14
実験手法SOLID-STATE NMR, SOLUTION NMR
主引用文献Conformational States of the Cytoprotective Protein Bcl-xL.
Biophys.J., 119, 2020
2JOW
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BU of 2jow by Molmil
Differences in the electrostatic surfaces of the type III secretion needle proteins
分子名称: Protein prgI
著者Wang, Y, Ouellette, A.N, Egan, C.W, De Guzman, R.N.
登録日2007-04-06
公開日2007-07-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Differences in the Electrostatic Surfaces of the Type III Secretion Needle Proteins PrgI, BsaL, and MxiH
J.Mol.Biol., 371, 2007
7KJZ
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BU of 7kjz by Molmil
crystal structure of PLEKHA7 PH domain biding inositol-tetraphosphate
分子名称: 1,2-ETHANEDIOL, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, Pleckstrin homology domain-containing family A member 7
著者Marassi, F.M, Aleshin, A.E, Liddington, R.C.
登録日2020-10-26
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
7KK7
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crystal structure of ligand-free PLEKHA7 PH domain
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pleckstrin homology domain-containing family A member 7
著者Marassi, F.M, Aleshin, A.E, Liddington, R.C.
登録日2020-10-27
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
7KJO
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crystal structure of PLEKHA7 PH domain biding SO4
分子名称: GLYCEROL, Pleckstrin homology domain-containing family A member 7, SULFATE ION
著者Marassi, F.M, Aleshin, A.E, Liddington, R.C.
登録日2020-10-26
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids.
Structure, 29, 2021
8TZ5
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Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with N-hydroxycytidine
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxycytidine, SODIUM ION, ...
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8W77
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Human Consensus Olfactory Receptor OR52c in apo state, OR52c only
分子名称: Human Consensus Olfactory Receptor OR52c in apo state, receptor only,Soluble cytochrome b562
著者Choi, C.W, Bae, J, Choi, H.-J, Kim, J.
登録日2023-08-30
公開日2023-12-20
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Understanding the molecular mechanisms of odorant binding and activation of the human OR52 family.
Nat Commun, 14, 2023
8TZ4
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Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, subset reconstruction
分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ6
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Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with PSI-6206
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2'-deoxy-2'-fluoro-2'-methyluridine, SODIUM ION, ...
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZD
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Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZA
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Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 2, INT2-INT1-INT1 conformation
分子名称: N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024
8TZ3
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Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Sodium/nucleoside cotransporter
著者Wright, N.J, Lee, S.-Y.
登録日2023-08-26
公開日2024-03-13
実験手法ELECTRON MICROSCOPY (2.31 Å)
主引用文献Antiviral drug recognition and elevator-type transport motions of CNT3.
Nat.Chem.Biol., 2024

 

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