8TZ3

Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with GS-441524, consensus reconstruction

Summary for 8TZ3

• Entry DOI: 10.2210/pdb8tz3/pdb
• EMDB information: 41732
• Descriptor: Sodium/nucleoside cotransporter, SODIUM ION, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ... (4 entities in total)
• Functional Keywords: membrane protein, transporter, nucleoside, transport protein
• Biological source: Bos taurus (cattle)
• Total number of polymer chains: 3
• Total formula weight: 247389.17

Authors

Wright, N.J.,Lee, S.-Y. (deposition date: 2023-08-26, release date: 2024-03-13)

• Primary citation: Wright, N.J.,Zhang, F.,Suo, Y.,Kong, L.,Yin, Y.,Fedor, J.G.,Sharma, K.,Borgnia, M.J.,Im, W.,Lee, S.Y.; Antiviral drug recognition and elevator-type transport motions of CNT3.; Nat.Chem.Biol., 2024; PubMed: 38418906; DOI: 10.1038/s41589-024-01559-8

Experimental method

ELECTRON MICROSCOPY (2.31 Å)