8TZD

Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-OFS conformation (3DVA analysis)

Summary for 8TZD

Entry DOI	10.2210/pdb8tzd/pdb
EMDB information	41755
Descriptor	Sodium/nucleoside cotransporter, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (3 entities in total)
Functional Keywords	membrane protein, transporter, nucleoside, transport protein
Biological source	Bos taurus (cattle)
Total number of polymer chains	3
Total formula weight	214982.95
Authors	Wright, N.J.,Lee, S.-Y. (deposition date: 2023-08-26, release date: 2024-03-13)
Primary citation	Wright, N.J.,Zhang, F.,Suo, Y.,Kong, L.,Yin, Y.,Fedor, J.G.,Sharma, K.,Borgnia, M.J.,Im, W.,Lee, S.Y. Antiviral drug recognition and elevator-type transport motions of CNT3. Nat.Chem.Biol., 2024 Cited by PubMed: 38418906 DOI: 10.1038/s41589-024-01559-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.2 Å)

Structure validation