8ET9

Cryo-EM structure of the organic cation transporter 2 in complex with 1-methyl-4-phenylpyridinium

Summary for 8ET9

Entry DOI	10.2210/pdb8et9/pdb
EMDB information	28589
Descriptor	OCT2, 1-methyl-4-phenylpyridin-1-ium (2 entities in total)
Functional Keywords	cation, transport, membrane protein, transport protein
Biological source	Homo sapiens
Total number of polymer chains	1
Total formula weight	62200.78
Authors	Suo, Y.,Wright, N.J.,Lee, S.-Y. (deposition date: 2022-10-16, release date: 2023-05-31, Last modification date: 2023-08-02)
Primary citation	Suo, Y.,Wright, N.J.,Guterres, H.,Fedor, J.G.,Butay, K.J.,Borgnia, M.J.,Im, W.,Lee, S.Y. Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2. Nat.Struct.Mol.Biol., 30:1001-1011, 2023 Cited by PubMed: 37291422 DOI: 10.1038/s41594-023-01017-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.61 Å)

Structure validation