7ANW
 
 | | hSARM1 NAD+ complex | | 分子名称: | NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Mim, C, Isupov, M.N, Zalk, R, Dessau, M, Hons, M, Opatowsky, Y. | | 登録日 | 2020-10-13 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
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6ZG0
 | | SARM1 SAM1-2 domains | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | | 登録日 | 2020-06-18 | | 公開日 | 2020-11-11 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
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6ZG1
 | | SARM1 SAM1-2 domains | | 分子名称: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | | 登録日 | 2020-06-18 | | 公開日 | 2020-11-11 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | | 主引用文献 | Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
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6ZFX
 | | hSARM1 GraFix-ed | | 分子名称: | (~{E})-4-methylnon-4-enedial, NAD(+) hydrolase SARM1 | | 著者 | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | | 登録日 | 2020-06-18 | | 公開日 | 2020-11-18 | | 最終更新日 | 2022-11-09 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
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6GGS
 | | Structure of RIP2 CARD filament | | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2 | | 著者 | Pellegrini, E, Cusack, S, Desfosses, A, Schoehn, G, Malet, H, Gutsche, I, Sachse, C, Hons, M. | | 登録日 | 2018-05-03 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.94 Å) | | 主引用文献 | RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling.
Nat Commun, 9, 2018
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8AOX
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8AXV
 | | Structure of an open form of CHIKV nsP1 capping pores | | 分子名称: | 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, ZINC ION, mRNA-capping enzyme nsP1 | | 著者 | Reguera, J, Jones, R, Hons, M. | | 登録日 | 2022-09-01 | | 公開日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8AOW
 | | CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with m7GTP and SAH ligands | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Jones, R, Hons, M, Reguera, J. | | 登録日 | 2022-08-08 | | 公開日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8APX
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8AOV
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7ZAY
 | | Human heparan sulfate polymerase complex EXT1-EXT2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Exostosin-1, Exostosin-2, ... | | 著者 | Leisico, F, Omeiri, J, Hons, M, Schoehn, G, Lortat-Jacob, H, Wild, R. | | 登録日 | 2022-03-23 | | 公開日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of the human heparan sulfate polymerase complex EXT1-EXT2.
Nat Commun, 13, 2022
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7QG0
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8P2M
 | | C. elegans TIR-1 protein. | | 分子名称: | NAD(+) hydrolase tir-1 | | 著者 | Isupov, M.N, Opatowsky, Y. | | 登録日 | 2023-05-16 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Structure-function analysis of ceTIR-1/hSARM1 explains the lack of Wallerian axonal degeneration in C. elegans.
Cell Rep, 42, 2023
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8P2L
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8QHC
 | | Cryo-EM structure of SidH from Legionella pneumophila in complex with LubX | | 分子名称: | E3 ubiquitin--protein ligase, Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Sharma, R, Adams, M, Bhogaraju, S. | | 登録日 | 2023-09-07 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
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6RLP
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8QFS
 | | Cryo-EM structure of SidH from Legionella pneumophila | | 分子名称: | Elongation factor Tu, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Sharma, R, Weis, F, Bhogaraju, S. | | 登録日 | 2023-09-04 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis for the toxicity of Legionella pneumophila effector SidH.
Nat Commun, 14, 2023
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8AZA
 | | Structure of RIP2K dimer bound to the XIAP BIR2 domain | | 分子名称: | E3 ubiquitin-protein ligase XIAP, Receptor-interacting serine/threonine-protein kinase 2, ZINC ION | | 著者 | Pellegrini, E, Cusack, S. | | 登録日 | 2022-09-05 | | 公開日 | 2022-10-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.
Life Sci Alliance, 6, 2023
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6GFJ
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