8AZA
Structure of RIP2K dimer bound to the XIAP BIR2 domain
Summary for 8AZA
Entry DOI | 10.2210/pdb8aza/pdb |
EMDB information | 15757 |
Descriptor | E3 ubiquitin-protein ligase XIAP, Receptor-interacting serine/threonine-protein kinase 2, ZINC ION (3 entities in total) |
Functional Keywords | kinase, bir2, complex, dimer, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 83120.68 |
Authors | Pellegrini, E.,Cusack, S. (deposition date: 2022-09-05, release date: 2022-10-26, Last modification date: 2023-09-20) |
Primary citation | Lethier, M.,Huard, K.,Hons, M.,Favier, A.,Brutscher, B.,Boeri Erba, E.,Abbott, D.W.,Cusack, S.,Pellegrini, E. Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface. Life Sci Alliance, 6:-, 2023 Cited by PubMed: 37673444DOI: 10.26508/lsa.202201784 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.15 Å) |
Structure validation
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