8AOW
CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with m7GTP and SAH ligands
Summary for 8AOW
Entry DOI | 10.2210/pdb8aow/pdb |
Related | 6Z0U |
EMDB information | 15554 |
Descriptor | mRNA-capping enzyme nsP1, ZINC ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total) |
Functional Keywords | alphavirus replication complex capping pores membrane pore methyltransferase gunayltransferase viral protein, viral protein |
Biological source | Chikungunya virus strain S27-African prototype |
Total number of polymer chains | 12 |
Total formula weight | 743797.42 |
Authors | Jones, R.,Hons, M.,Reguera, J. (deposition date: 2022-08-08, release date: 2023-03-29, Last modification date: 2024-07-24) |
Primary citation | Jones, R.,Hons, M.,Rabah, N.,Zamarreno, N.,Arranz, R.,Reguera, J. Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores. Proc.Natl.Acad.Sci.USA, 120:e2213934120-e2213934120, 2023 Cited by PubMed: 36913573DOI: 10.1073/pnas.2213934120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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