8AOV

CryoEM structure of the Chikungunya virus nsP1 capping pores in complex with GTP

Summary for 8AOV

• Entry DOI: 10.2210/pdb8aov/pdb
• Related: 6Z0V
• EMDB information: 15553
• Descriptor: mRNA-capping enzyme nsP1, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: alphavirus replication complex capping pores membrane pore methyltransferase guanylyl transferase, viral protein
• Biological source: Chikungunya virus strain S27-African prototype
• Total number of polymer chains: 12
• Total formula weight: 738420.74

Authors

Jones, R.,Hons, M.,Reguera, J. (deposition date: 2022-08-08, release date: 2023-05-31)

• Primary citation: Jones, R.,Hons, M.,Rabah, N.,Zamarreno, N.,Arranz, R.,Reguera, J.; Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.; Proc.Natl.Acad.Sci.USA, 120:e2213934120-e2213934120, 2023; PubMed: 36913573; DOI: 10.1073/pnas.2213934120

Experimental method

ELECTRON MICROSCOPY (2.48 Å)