8AXV

Structure of an open form of CHIKV nsP1 capping pores

Summary for 8AXV

• Entry DOI: 10.2210/pdb8axv/pdb
• Related: 6Z0U 8AOV 8AOW 8AOX 8APX
• EMDB information: 15704
• Descriptor: mRNA-capping enzyme nsP1, ZINC ION, 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one (3 entities in total)
• Functional Keywords: alphavirus replication complex, capping pores, membrane pore, methyltransferase, guanylyl transferase, viral prot, viral protein
• Biological source: Chikungunya virus strain S27-African prototype
• Total number of polymer chains: 12
• Total formula weight: 722471.81

Authors

Reguera, J.,Jones, R.,Hons, M. (deposition date: 2022-09-01, release date: 2023-03-29)

• Primary citation: Jones, R.,Hons, M.,Rabah, N.,Zamarreno, N.,Arranz, R.,Reguera, J.; Structural basis and dynamics of Chikungunya alphavirus RNA capping by nsP1 capping pores.; Proc.Natl.Acad.Sci.USA, 120:e2213934120-e2213934120, 2023; PubMed: 36913573; DOI: 10.1073/pnas.2213934120

Experimental method

ELECTRON MICROSCOPY (2.8 Å)