6GFJ

Structure of RIP2 CARD domain fused to crystallisable MBP tag

Summary for 6GFJ

Entry DOI	10.2210/pdb6gfj/pdb
Related PRD ID	PRD_900001
Descriptor	Sugar ABC transporter substrate-binding protein,Receptor-interacting serine/threonine-protein kinase 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose (2 entities in total)
Functional Keywords	card, crystallographic mbp, rip2, death domain, transferase
Biological source	Methanosarcina mazei (Methanosarcina frisia) More
Total number of polymer chains	4
Total formula weight	212032.31
Authors	Pellegrini, E.,Cusack, S. (deposition date: 2018-04-30, release date: 2019-03-13, Last modification date: 2024-01-17)
Primary citation	Pellegrini, E.,Desfosses, A.,Wallmann, A.,Schulze, W.M.,Rehbein, K.,Mas, P.,Signor, L.,Gaudon, S.,Zenkeviciute, G.,Hons, M.,Malet, H.,Gutsche, I.,Sachse, C.,Schoehn, G.,Oschkinat, H.,Cusack, S. RIP2 filament formation is required for NOD2 dependent NF-kappa B signalling. Nat Commun, 9:4043-4043, 2018 Cited by PubMed: 30279485 DOI: 10.1038/s41467-018-06451-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation