7ZAY

Human heparan sulfate polymerase complex EXT1-EXT2

Summary for 7ZAY

• Entry DOI: 10.2210/pdb7zay/pdb
• EMDB information: 14582
• Descriptor: Exostosin-1, Exostosin-2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: heparan sulfate biosynthesis, enzyme complex, glycosyltransferase, golgi, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 165530.61

Authors

Leisico, F.,Omeiri, J.,Hons, M.,Schoehn, G.,Lortat-Jacob, H.,Wild, R. (deposition date: 2022-03-23, release date: 2022-12-07)

• Primary citation: Leisico, F.,Omeiri, J.,Le Narvor, C.,Beaudouin, J.,Hons, M.,Fenel, D.,Schoehn, G.,Coute, Y.,Bonnaffe, D.,Sadir, R.,Lortat-Jacob, H.,Wild, R.; Structure of the human heparan sulfate polymerase complex EXT1-EXT2.; Nat Commun, 13:7110-7110, 2022; PubMed: 36402845; DOI: 10.1038/s41467-022-34882-6

Experimental method

ELECTRON MICROSCOPY (2.8 Å)