5G46
| Ligand complex of RORg LBD | 分子名称: | 2-ETHYL-4(1H)-QUINOLINONE, NUCLEAR RECEPTOR ROR-GAMMA, RORG, ... | 著者 | Xue, Y, Guo, H, Hillertz, P. | 登録日 | 2016-05-04 | 公開日 | 2016-08-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Fragment Screening of Rorgammat Using Cocktail Crystallography: Identification of Simultaneous Binding of Multiple Fragments. Chemmedchem, 11, 2016
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5G43
| Ligand complex of RORg LBD | 分子名称: | 2-(1-PIPERIDINYL)-1,3-THIAZOL-4-AMINE, NUCLEAR RECEPTOR ROR-GAMMA, RORG | 著者 | Xue, Y, Guo, H, Hillertz, P. | 登録日 | 2016-05-04 | 公開日 | 2016-08-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Fragment Screening of Rorgammat Using Cocktail Crystallography: Identification of Simultaneous Binding of Multiple Fragments. Chemmedchem, 11, 2016
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5G44
| Ligand complex of RORg LBD | 分子名称: | (4-pyrimidin-5-ylphenyl)methanol, 4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide, 8-methoxy-2,3-dimethylquinoxalin-5-ol, ... | 著者 | Xue, Y, Guo, H, Hillertz, P. | 登録日 | 2016-05-04 | 公開日 | 2016-08-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Fragment Screening of Rorgammat Using Cocktail Crystallography: Identification of Simultaneous Binding of Multiple Fragments. Chemmedchem, 11, 2016
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8HNI
| hnRNP A2/B1 RRMs in complex with telomeric DNA | 分子名称: | DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3'), Heterogeneous nuclear ribonucleoproteins A2/B1 | 著者 | Liu, Y, Abula, A, Xiao, H, Guo, H, Li, T, Zheng, L, Chen, B, Nguyen, H, Ji, X. | 登録日 | 2022-12-07 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.644 Å) | 主引用文献 | Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition. J.Mol.Biol., 435, 2023
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5XBM
| Structure of SCARB2-JL2 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosome membrane protein 2, ... | 著者 | Zhang, X, Yang, P, Wang, N, Zhang, J, Li, J, Guo, H, Yin, X, Rao, Z, Wang, X, Zhang, L. | 登録日 | 2017-03-20 | 公開日 | 2018-06-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.501 Å) | 主引用文献 | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection. Protein Cell, 8, 2017
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7VPG
| Crystal structure of the C-terminal tail of SARS-CoV-1 Orf6 complex with human nucleoporin pair Rae1-Nup98 | 分子名称: | Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor | 著者 | Li, T, Guo, H, Yang, T, Wen, Y, Ji, X. | 登録日 | 2021-10-17 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export. Front Mol Biosci, 8, 2021
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7VPH
| Crystal structure of the C-terminal tail of SARS-CoV-2 Orf6 complex with human nucleoporin pair Rae1-Nup98 | 分子名称: | Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor | 著者 | Li, T, Guo, H, Yang, T, Wen, Y, Ji, X. | 登録日 | 2021-10-17 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export. Front Mol Biosci, 8, 2021
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7WM3
| hnRNP A2/B1 RRMs in complex with single-stranded DNA | 分子名称: | DNA (5'-D(P*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), Heterogeneous nuclear ribonucleoproteins A2/B1 | 著者 | Abula, A, Liu, Y, Guo, H, Li, T, Ji, X. | 登録日 | 2022-01-14 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structural Insight Into hnRNP A2/B1 Homodimerization and DNA Recognition. J.Mol.Biol., 435, 2022
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6JON
| Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, Primase | 著者 | Guo, H.J, Li, M.J, Wu, H, Yu, F, He, J.H. | 登録日 | 2019-03-22 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Crystal structures of phage NrS-1 N300-dNTPs-Mg2+complex provide molecular mechanisms for substrate specificity. Biochem.Biophys.Res.Commun., 515, 2019
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6JOP
| Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity | 分子名称: | MAGNESIUM ION, Primase, THYMIDINE-5'-TRIPHOSPHATE | 著者 | Guo, H.J, Li, M.J, Wu, H, Yu, F, He, J.H. | 登録日 | 2019-03-22 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | 主引用文献 | Crystal structures of phage NrS-1 N300-dNTPs-Mg2+complex provide molecular mechanisms for substrate specificity. Biochem.Biophys.Res.Commun., 515, 2019
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6JOQ
| Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Primase | 著者 | Guo, H.J, Li, M.J, Wu, H, Yu, F, He, J.H. | 登録日 | 2019-03-22 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of phage NrS-1 N300-dNTPs-Mg2+complex provide molecular mechanisms for substrate specificity. Biochem.Biophys.Res.Commun., 515, 2019
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4Q5U
| Structure of calmodulin bound to its recognition site from calcineurin | 分子名称: | CALCIUM ION, Calmodulin, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 著者 | Guo, H, Dunlap, T.B, Creamer, T.P, Vander Kooi, C.W. | 登録日 | 2014-04-17 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Stoichiometry of the calcineurin regulatory domain-calmodulin complex. Biochemistry, 53, 2014
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6AX7
| The crystal structure of a lysyl hydroxylase from Acanthamoeba polyphaga mimivirus | 分子名称: | FE (II) ION, Procollagen lysyl hydroxylase and glycosyltransferase | 著者 | Guo, H, Tsai, C, Miller, M.D, Alvarado, S, Tainer, J.A, Phillips Jr, G.N, Kurie, J.M. | 登録日 | 2017-09-06 | 公開日 | 2018-02-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | 主引用文献 | Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding. Nat Commun, 9, 2018
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6AX6
| The crystal structure of a lysyl hydroxylase from Acanthamoeba polyphaga mimivirus | 分子名称: | FE (II) ION, IODIDE ION, Procollagen lysyl hydroxylase and glycosyltransferase | 著者 | Guo, H, Tsai, C, Miller, M.D, Alvarado, S, Tainer, J.A, Phillips Jr, G.N, Kurie, J.M. | 登録日 | 2017-09-06 | 公開日 | 2018-02-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.241 Å) | 主引用文献 | Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding. Nat Commun, 9, 2018
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4FLB
| CID of human RPRD2 | 分子名称: | PRASEODYMIUM ION, Regulation of nuclear pre-mRNA domain-containing protein 2, SULFATE ION, ... | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | 登録日 | 2012-06-14 | 公開日 | 2012-08-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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4FLA
| Crystal structure of human RPRD1B, carboxy-terminal domain | 分子名称: | Regulation of nuclear pre-mRNA domain-containing protein 1B, UNKNOWN ATOM OR ION | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | 登録日 | 2012-06-14 | 公開日 | 2012-08-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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4Q96
| CID of human RPRD1B in complex with an unmodified CTD peptide | 分子名称: | RPB1-CTD, Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, ... | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | 登録日 | 2014-04-29 | 公開日 | 2014-06-04 | 最終更新日 | 2014-08-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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4G3Y
| Crystal structure of TNF-alpha in complex with Infliximab Fab fragment | 分子名称: | Tumor necrosis factor, infliximab Fab H, infliximab Fab L | 著者 | Liang, S.Y, Dai, J.X, Guo, Y.J, Lou, Z.Y. | 登録日 | 2012-07-15 | 公開日 | 2013-03-27 | 最終更新日 | 2013-08-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for treating tumor necrosis factor alpha (TNFalpha)-associated diseases with the therapeutic antibody infliximab J.Biol.Chem., 288, 2013
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4JXT
| CID of human RPRD1A in complex with a phosphorylated peptide from RPB1-CTD | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Regulation of nuclear pre-mRNA domain-containing protein 1A, UNKNOWN ATOM OR ION | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Guo, X, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | 登録日 | 2013-03-28 | 公開日 | 2013-11-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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4Q94
| human RPRD1B CID in complex with a RPB1-CTD derived Ser2 phosphorylated peptide | 分子名称: | Regulation of nuclear pre-mRNA domain-containing protein 1B, SULFATE ION, UNKNOWN ATOM OR ION, ... | 著者 | Ni, Z, Xu, C, Tempel, W, El Bakkouri, M, Loppnau, P, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Greenblatt, J.F, Structural Genomics Consortium (SGC) | 登録日 | 2014-04-29 | 公開日 | 2014-06-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation. Nat.Struct.Mol.Biol., 21, 2014
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6QLY
| IDOL FERM domain | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase MYLIP, SULFATE ION | 著者 | Martinelli, L, Sixma, T.K. | 登録日 | 2019-02-01 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. J.Biol.Chem., 295, 2020
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3NFS
| Crystal structure the Fab fragment of therapeutic antibody daclizumab | 分子名称: | Heavy chain of Fab fragment of daclizumab, Light chain of Fab fragment of daclizumab | 著者 | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | 登録日 | 2010-06-10 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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3NFP
| Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain | 分子名称: | Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab | 著者 | Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. | 登録日 | 2010-06-10 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
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3IU3
| Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain | 分子名称: | Heavy chain of Fab fragment of Basiliximab, Interleukin-2 receptor alpha chain, Light chain of Fab fragment of Basiliximab, ... | 著者 | Du, J, Yang, H, Wang, J, Ding, J. | 登録日 | 2009-08-29 | 公開日 | 2010-01-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for the blockage of IL-2 signaling by therapeutic antibody basiliximab J.Immunol., 184, 2010
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1B0R
| CRYSTAL STRUCTURE OF HLA-A*0201 COMPLEXED WITH A PEPTIDE WITH THE CARBOXYL-TERMINAL GROUP SUBSTITUTED BY A METHYL GROUP | 分子名称: | PROTEIN (HLA-A*0201), PROTEIN (INFLUENZA MATRIX PEPTIDE) | 著者 | Bouvier, M, Guo, H, Smith, K.J, Wiley, D.C. | 登録日 | 1998-11-12 | 公開日 | 1999-11-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of HLA-A*0201 complexed with antigenic peptides with either the amino- or carboxyl-terminal group substituted by a methyl group. Proteins, 33, 1998
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