7VPG

Crystal structure of the C-terminal tail of SARS-CoV-1 Orf6 complex with human nucleoporin pair Rae1-Nup98

Summary for 7VPG

• Entry DOI: 10.2210/pdb7vpg/pdb
• Descriptor: mRNA export factor, Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, ... (4 entities in total)
• Functional Keywords: complex, coronavirus, rna nuclear export, viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 211368.70

Authors

Li, T.,Guo, H.,Yang, T.,Wen, Y.,Ji, X. (deposition date: 2021-10-17, release date: 2022-01-19, Last modification date: 2023-11-29)

• Primary citation: Li, T.,Wen, Y.,Guo, H.,Yang, T.,Yang, H.,Ji, X.; Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export.; Front Mol Biosci, 8:813248-813248, 2021; PubMed: 35096974; DOI: 10.3389/fmolb.2021.813248

Experimental method

X-RAY DIFFRACTION (2.49 Å)