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7VPH

Crystal structure of the C-terminal tail of SARS-CoV-2 Orf6 complex with human nucleoporin pair Rae1-Nup98

Summary for 7VPH
Entry DOI10.2210/pdb7vph/pdb
DescriptormRNA export factor, Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, ... (4 entities in total)
Functional Keywordscomplex, coronavirus, rna nuclear export, protein binding, viral protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains12
Total formula weight210683.66
Authors
Li, T.,Guo, H.,Yang, T.,Wen, Y.,Ji, X. (deposition date: 2021-10-17, release date: 2022-01-19, Last modification date: 2023-11-29)
Primary citationLi, T.,Wen, Y.,Guo, H.,Yang, T.,Yang, H.,Ji, X.
Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export.
Front Mol Biosci, 8:813248-813248, 2021
Cited by
PubMed: 35096974
DOI: 10.3389/fmolb.2021.813248
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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