7VPH
Crystal structure of the C-terminal tail of SARS-CoV-2 Orf6 complex with human nucleoporin pair Rae1-Nup98
Summary for 7VPH
Entry DOI | 10.2210/pdb7vph/pdb |
Descriptor | mRNA export factor, Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, ... (4 entities in total) |
Functional Keywords | complex, coronavirus, rna nuclear export, protein binding, viral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 210683.66 |
Authors | |
Primary citation | Li, T.,Wen, Y.,Guo, H.,Yang, T.,Yang, H.,Ji, X. Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export. Front Mol Biosci, 8:813248-813248, 2021 Cited by PubMed: 35096974DOI: 10.3389/fmolb.2021.813248 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report