5G44

Ligand complex of RORg LBD

Summary for 5G44

Entry DOI	10.2210/pdb5g44/pdb
Related	5G42 5G43 5G45 5G46
Descriptor	NUCLEAR RECEPTOR ROR-GAMMA, RORG, 8-methoxy-2,3-dimethylquinoxalin-5-ol, ... (8 entities in total)
Functional Keywords	dna binding protein, rorg ligand, fragment screen, structure-based design, simultaneous binding
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus : P51449
Total number of polymer chains	2
Total formula weight	33141.07
Authors	Xue, Y.,Guo, H.,Hillertz, P. (deposition date: 2016-05-04, release date: 2016-08-03, Last modification date: 2016-09-28)
Primary citation	Xue, Y.,Guo, H.,Hillertz, P. Fragment Screening of Rorgammat Using Cocktail Crystallography: Identification of Simultaneous Binding of Multiple Fragments. Chemmedchem, 11:1881-, 2016 Cited by PubMed: 27432277 DOI: 10.1002/CMDC.201600242 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation