5G44

Ligand complex of RORg LBD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE I6G A 1510

Chain	Residue
A	HIS323
A	MET365
A	VAL376
A	PHE377
A	PHE378
A	PHE388
A	ILE397
A	SWX1511

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SWX A 1511

Chain	Residue
A	I6G1510
A	YTZ1512
A	HOH2046
A	ALA327

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site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE YTZ A 1512

Chain	Residue
A	GLN286
A	LEU287
A	ALA327
A	VAL361
A	ARG364
A	MET365
A	ARG367
A	ALA368
A	PHE377
A	SWX1511
A	HOH2011
A	HOH2047
A	HOH2049

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 1513

Chain	Residue
A	CYS366
A	TYR369
A	SER408
A	HOH2022

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DMS A 1514

Chain	Residue
A	GLN329
A	PRO499
A	PRO500
A	LEU501
A	HOH2117
A	HOH2139
C	ILE689

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