3J9Q
 
 | | Atomic structures of a bactericidal contractile nanotube in its pre- and post-contraction states | | Descriptor: | sheath, tube | | Authors: | Ge, P, Scholl, D, Leiman, P.G, Yu, X, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2015-02-17 | | Release date: | 2015-04-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states.
Nat.Struct.Mol.Biol., 22, 2015
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2WYY
 | | CRYOEM MODEL OF THE VESICULAR STOMATITIS VIRUS | | Descriptor: | NUCLEOPROTEIN, POLY-URIDINE | | Authors: | Ge, P, Tsao, J, Green, T.J, Luo, M, Zhou, Z.H. | | Deposit date: | 2009-11-20 | | Release date: | 2010-02-16 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (10.6 Å) | | Cite: | Cryo-Em Model of the Bullet-Shaped Vesicular Stomatitis Virus.
Science, 327, 2010
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6PYT
 | | CryoEM Structure of Pyocin R2 - precontracted - trunk | | Descriptor: | Pyocin sheath PA0622, Pyocin tube PA0623 | | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2019-07-30 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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3J06
 | | CryoEM Helical Reconstruction of TMV | | Descriptor: | 5'-R(P*AP*UP*G)-3', Coat protein | | Authors: | Ge, P, Zhou, Z.H. | | Deposit date: | 2011-04-26 | | Release date: | 2011-06-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Hydrogen-bonding networks and RNA bases revealed by cryo electron microscopy suggest a triggering mechanism for calcium switches.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3J9R
 | | Atomic structures of a bactericidal contractile nanotube in its pre- and post-contraction states | | Descriptor: | sheath | | Authors: | Ge, P, Scholl, D, Leiman, P.G, Yu, X, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2015-02-17 | | Release date: | 2015-04-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Atomic structures of a bactericidal contractile nanotube in its pre- and postcontraction states.
Nat.Struct.Mol.Biol., 22, 2015
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6U5B
 | | CryoEM Structure of Pyocin R2 - precontracted - baseplate | | Descriptor: | Glue PA0627, Ripcord PA0626, Sheath Initiator PA0617, ... | | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2019-08-27 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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6U5H
 | | CryoEM Structure of Pyocin R2 - precontracted - hub | | Descriptor: | Probable bacteriophage protein Pyocin R2 | | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2019-08-27 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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6U5K
 | | CryoEM Structure of Pyocin R2 - postcontracted - baseplate | | Descriptor: | Glue PA0627, Sheath Initiator PA0617, Sheath PA0622, ... | | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2019-08-27 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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6U5F
 | | CryoEM Structure of Pyocin R2 - precontracted - collar | | Descriptor: | Collar PA0615, Sheath PA0622, Tube PA0623 | | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2019-08-27 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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6U5J
 | | CryoEM Structure of Pyocin R2 - postcontracted - collar | | Descriptor: | Collar PA0615, Sheath PA0622 | | Authors: | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | | Deposit date: | 2019-08-27 | | Release date: | 2020-04-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Action of a minimal contractile bactericidal nanomachine.
Nature, 580, 2020
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6UUR
 | | Human prion protein fibril, M129 variant | | Descriptor: | Major prion protein | | Authors: | Glynn, C, Sawaya, M.R, Ge, P, Zhou, Z.H, Rodriguez, J.A. | | Deposit date: | 2019-10-31 | | Release date: | 2020-04-15 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of a human prion fibril with a hydrophobic, protease-resistant core.
Nat.Struct.Mol.Biol., 27, 2020
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3J2P
 | | CryoEM structure of Dengue virus envelope protein heterotetramer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Zhang, X, Ge, P, Yu, X, Brannan, J.M, Bi, G, Zhang, Q, Schein, S, Zhou, Z.H. | | Deposit date: | 2012-11-30 | | Release date: | 2012-12-19 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the mature dengue virus at 3.5-A resolution.
Nat.Struct.Mol.Biol., 20, 2012
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6N9Y
 | | Atomic structure of Non-Structural protein 1 of bluetongue virus | | Descriptor: | Non-structural protein 1 | | Authors: | Kerviel, A, Ge, P, Lai, M, Jih, J, Boyce, M, Zhang, X, Zhou, Z.H, Roy, P. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Atomic structure of the translation regulatory protein NS1 of bluetongue virus.
Nat Microbiol, 4, 2019
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6CU8
 | | Alpha Synuclein fibril formed by full length protein - Twister Polymorph | | Descriptor: | Alpha-synuclein | | Authors: | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | | Deposit date: | 2018-03-23 | | Release date: | 2018-09-12 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
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6CU7
 | | Alpha Synuclein fibril formed by full length protein - Rod Polymorph | | Descriptor: | Alpha-synuclein | | Authors: | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | | Deposit date: | 2018-03-23 | | Release date: | 2018-09-12 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
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8DU2
 | | HnRNPA2 D290V LCD PM1 | | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | | Deposit date: | 2022-07-26 | | Release date: | 2023-08-02 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
J.Biol.Chem., 300, 2023
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8DUW
 | | HnRNPA2 D290V LCD PM2 | | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | | Deposit date: | 2022-07-27 | | Release date: | 2023-08-02 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
J.Biol.Chem., 300, 2023
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8TER
 | | Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) P285L mutant, amyloid fiber | | Descriptor: | TRK-fused gene protein Low Complexity Domain P285L mutant | | Authors: | Rosenberg, G.M, Sawaya, M.R, Boyer, D.R, Ge, P, Abskharon, R, Eisenberg, D.S. | | Deposit date: | 2023-07-06 | | Release date: | 2023-12-20 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.59 Å) | | Cite: | Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method.
Pnas Nexus, 2, 2023
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8TEQ
 | | Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) G269V mutant, amyloid fiber | | Descriptor: | TRK-fused gene protein Low Complexity Domain G269V mutant | | Authors: | Rosenberg, G.M, Sawaya, M.R, Boyer, D.R, Ge, P, Abskharon, R, Eisenberg, D.S. | | Deposit date: | 2023-07-06 | | Release date: | 2023-12-20 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method.
Pnas Nexus, 2, 2023
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8EC7
 | | HnRNPA2 D290V LCD PM3 | | Descriptor: | Heterogeneous nuclear ribonucleoproteins A2/B1 | | Authors: | Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R. | | Deposit date: | 2022-09-01 | | Release date: | 2023-09-06 | | Last modified: | 2024-02-14 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
J.Biol.Chem., 300, 2023
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9B4J
 | | Filament of D-TLKIVWS, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | Descriptor: | DTH-DLE-DLY-DIL-DVA-DTR-DSN | | Authors: | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2024-03-20 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.
Biorxiv, 2024
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9B4K
 | | Filament of D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | Descriptor: | DTH-DLE-DLY-DIL-DVA-DTR-DAR | | Authors: | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2024-03-20 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.
Biorxiv, 2024
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9B4O
 | | Alzheimer's Tau Paired Helical Filaments, determined by CryoEM, before addition of D-peptide disaggregants | | Descriptor: | Microtubule-associated protein tau | | Authors: | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2024-03-21 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.
Biorxiv, 2024
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9B4I
 | | Filament of D-TLKIVWI, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | Descriptor: | DTH-DLE-DLY-DIL-DVA-DTR-DIL | | Authors: | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2024-03-20 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.
Biorxiv, 2024
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9B4N
 | | Filament of Tau in complex with D-TLKIVWR, a D-peptide that disaggregates Alzheimer's Paired Helical Filaments, determined by Cryo-EM | | Descriptor: | Microtubule-associated protein tau | | Authors: | Hou, K, Ge, P, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2024-03-21 | | Release date: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism.
Biorxiv, 2024
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