5WXF
| Crystal structure of uPA in complex with upain-2-2 | Descriptor: | SULFATE ION, Urokinase-type plasminogen activator chain B, upain-2-2 peptide | Authors: | Jiang, L, Huang, M. | Deposit date: | 2017-01-07 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862, 2018
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5WXR
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5WXO
| Crystal structure of uPA in complex with upain-2-2-W3A | Descriptor: | Urokinase-type plasminogen activator chain B, upain-2-2-W3A peptide | Authors: | Jiang, L, Huang, M. | Deposit date: | 2017-01-08 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862, 2018
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5WXS
| Crystal structure of uPA in complex with S2444 | Descriptor: | (2R)-N-[2-[[(2S)-5-carbamimidamido-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-5-oxidanylidene-1,2-dihydropyrrole-2-carboxamide, Urokinase-type plasminogen activator chain B | Authors: | Jiang, L, Huang, M. | Deposit date: | 2017-01-08 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of uPA in complex with S2444 To Be Published
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3M61
| Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition | Descriptor: | Urokinase-type plasminogen activator, upain-1 W3A | Authors: | Jiang, L, Yuan, C, Wind, T, Andreasen, P.A, Chen, L, Meehan, E.J, Huang, M. | Deposit date: | 2010-03-15 | Release date: | 2010-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal structure of complex of urokinase and a upain-1 variant(W3A) in pH4.6 condition TO BE PUBLISHED
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4X1N
| The crystal structure of mupain-1-16 in complex with murinised human uPA at pH7.4 | Descriptor: | Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide | Authors: | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | Deposit date: | 2014-11-25 | Release date: | 2015-03-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X1Q
| The crystal structure of mupain-1 in complex with murinised human uPA at pH7.4 | Descriptor: | Urokinase-type plasminogen activator, mupain-1 | Authors: | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | Deposit date: | 2014-11-25 | Release date: | 2015-03-25 | Last modified: | 2015-11-04 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X0W
| The crystal structure of mupain-1-17 in complex with murinised human uPA | Descriptor: | SULFATE ION, Urokinase-type plasminogen activator, mupain-1-17, ... | Authors: | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | Deposit date: | 2014-11-24 | Release date: | 2015-10-21 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. Int.J.Biochem.Cell Biol., 62, 2015
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4X1P
| The crystal structure of mupain-1-17 in complex with murinised human uPA at pH4.6 | Descriptor: | MUPAIN-1-17, SULFATE ION, TRIETHYLENE GLYCOL, ... | Authors: | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | Deposit date: | 2014-11-25 | Release date: | 2015-10-21 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Distinctive binding modes and inhibitory mechanisms of two peptidic inhibitors of urokinase-type plasminogen activator with isomeric P1 residues. Int.J.Biochem.Cell Biol., 62, 2015
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4X1S
| The crystal structure of mupain-1-16-D9A in complex with murinised human uPA at pH7.4 | Descriptor: | Urokinase-type plasminogen activator, mupain-1-16, piperidine-1-carboximidamide | Authors: | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | Deposit date: | 2014-11-25 | Release date: | 2015-10-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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4X1R
| The crystal structure of mupain-1-12 in complex with murinised human uPA at pH7.4 | Descriptor: | 1-phenylguanidine, Urokinase-type plasminogen activator, mupain-1-12 | Authors: | Jiang, L, Zhao, B, Xu, P, Andreasen, P, Huang, M. | Deposit date: | 2014-11-25 | Release date: | 2015-03-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A cyclic peptidic serine protease inhibitor: increasing affinity by increasing peptide flexibility. Plos One, 9, 2014
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3BBX
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3BBU
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3BBV
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4DVB
| The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | Descriptor: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-23 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
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4DVA
| The crystal structure of human urokinase-type plasminogen activator catalytic domain | Descriptor: | HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-23 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody Biochem.J., 449, 2013
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4DW2
| The crystal structure of uPA in complex with the Fab fragment of mAb-112 | Descriptor: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-24 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
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2TOB
| SOLUTION STRUCTURE OF THE TOBRAMYCIN-RNA APTAMER COMPLEX, NMR, 13 STRUCTURES | Descriptor: | 1,3-DIAMINO-4,5,6-TRIHYDROXY-CYCLOHEXANE, 2,6-diammonio-2,3,6-trideoxy-alpha-D-glucopyranose, 3-ammonio-3-deoxy-alpha-D-glucopyranose, ... | Authors: | Jiang, L, Patel, D.J. | Deposit date: | 1998-06-17 | Release date: | 1999-06-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the tobramycin-RNA aptamer complex. Nat.Struct.Biol., 5, 1998
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1TOB
| SACCHARIDE-RNA RECOGNITION IN AN AMINOGLYCOSIDE ANTIBIOTIC-RNA APTAMER COMPLEX, NMR, 7 STRUCTURES | Descriptor: | 1,3-DIAMINO-5,6-DIHYDROXYCYCLOHEXANE, 2,6-diammonio-2,3,6-trideoxy-alpha-D-glucopyranose, 3-ammonio-3-deoxy-alpha-D-glucopyranose, ... | Authors: | Jiang, L, Suri, A.K, Fiala, R, Patel, D.J. | Deposit date: | 1996-12-12 | Release date: | 1997-06-16 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex. Chem.Biol., 4, 1997
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1NEM
| Saccharide-RNA recognition in the neomycin B / RNA aptamer complex | Descriptor: | 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranose, 2,6-diamino-2,6-dideoxy-beta-L-idopyranose-(1-3)-beta-D-ribofuranose, 2-DEOXY-D-STREPTAMINE, ... | Authors: | Jiang, L, Majumdar, A, Hu, W, Jaishree, T.J, Xu, W, Patel, D.J. | Deposit date: | 1999-03-15 | Release date: | 1999-08-31 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer Structure Fold.Des., 7, 1999
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4ZKR
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4ZKS
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4ZKN
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4ZHL
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4ZHM
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